TY - JOUR
T1 - A case of legionellosis during treatment with a TNFα antagonist
AU - Wondergem, Marielle J.
AU - Voskuyl, Alexander E.
AU - van Agtmael, Michiel A.
PY - 2004
Y1 - 2004
N2 - We report a patient with Legionella pneumophila pneumonia after infliximab therapy for rheumatoid arthritis. Arguments are discussed for an emerging incidence of infections with intracellular microorganisms, granulomatous and non-granulomatous, in patients having received anti-TNFα therapy. These discussions consist of clinical and epidemiological data, experimental data in animals, theoretical evidence, and we provide a possible pathogenetic mechanism.
AB - We report a patient with Legionella pneumophila pneumonia after infliximab therapy for rheumatoid arthritis. Arguments are discussed for an emerging incidence of infections with intracellular microorganisms, granulomatous and non-granulomatous, in patients having received anti-TNFα therapy. These discussions consist of clinical and epidemiological data, experimental data in animals, theoretical evidence, and we provide a possible pathogenetic mechanism.
UR - http://www.scopus.com/inward/record.url?scp=2642553833&partnerID=8YFLogxK
U2 - 10.1080/00365540410019598
DO - 10.1080/00365540410019598
M3 - Article
C2 - 15198192
AN - SCOPUS:2642553833
VL - 36
SP - 310
EP - 311
JO - Scandinavian Journal of Infectious Diseases
JF - Scandinavian Journal of Infectious Diseases
SN - 0036-5548
IS - 4
ER -