Abstract
BACKGROUND: Cisplatin is considered safe to use during the second and third trimesters of pregnancy in patients with cancer.
CASE: A 34-year-old pregnant woman was diagnosed with cervical cancer. She received five weekly dosages of cisplatin and paclitaxel, starting at 26 5/7 weeks of gestation. An elective cesarean delivery was performed at 34 4/7 weeks of gestation. After birth, the neonate was diagnosed with severe bilateral perceptive hearing loss.
CONCLUSION: Cisplatin during the second and third trimesters of pregnancy may lead to fetal ototoxicity.
| Original language | English |
|---|---|
| Pages (from-to) | 454-6 |
| Number of pages | 3 |
| Journal | Obstetrics and Gynecology |
| Volume | 124 |
| Issue number | 2 Pt 2 Suppl 1 |
| DOIs | |
| Publication status | Published - Aug 2014 |
| Externally published | Yes |
Cite this
Geijteman, E. C. T., Wensveen, C. W. M., Duvekot, J. J., & van Zuylen, L. (2014). A child with severe hearing loss associated with maternal cisplatin treatment during pregnancy. Obstetrics and Gynecology, 124(2 Pt 2 Suppl 1), 454-6. https://doi.org/10.1097/AOG.0000000000000389