A multimodal day treatment program for multi-problem young adults: Study protocol for a randomized controlled trial

Marie Jolette A. Luijks, Floor Bevaart, Josjan Zijlmans, Laura van Duin, Reshmi Marhe, Theo A.H. Doreleijers, Henning Tiemeier, Jessica J. Asscher, Arne Popma

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: Effective interventions for young adults with severe, multiple problems - such as psychosocial and psychiatric problems, delinquency, unemployment and substance use - are scarce but urgently needed in order to support an adequate transition to adulthood. A multimodal day treatment program called "New Opportunities" (in Dutch: "De Nieuwe Kans"; DNK) was specifically developed to target multi-problem young adults in The Netherlands. The aim of this study protocol is to describe the design of a randomized controlled trial (RCT) in clinical practice to examine the effectiveness of DNK in comparison with care as usual (CAU). Methods/design: Multi-problem young adults in Rotterdam, The Netherlands, will be assigned randomly to DNK (expected N = 150) and CAU (expected N = 150). Primary outcome measures are recidivism and self-sufficiency. Secondary outcome measures include quality of life, attending school/work, psychological functioning, cognitive distortions and substance use. Participant and program characteristics will be examined as potential moderators of effectiveness. Additionally, cost-effectiveness will be measured. During 14 months, data from multiple resources will be collected at four time points. Discussion: This study is one of the first RCTs on the effectiveness of interventions developed for multi-problem young adults. The results will contribute to the currently scant knowledge about what works for various multi-problem young adults in their transition to adulthood. In addition, the study protocol will provide insight into implementing an RCT in a dynamic setting of clinical practice. Trial registration: Dutch Trial Register, identifier: NTR5163. Registered on 17 April 2015; retrospectively registered during the recruitment phase.

Original languageEnglish
Article number225
JournalTrials
Volume18
Issue number1
DOIs
Publication statusPublished - 19 May 2017

Cite this

@article{69b2469cc42d4ec6862e981ff81ee4cb,
title = "A multimodal day treatment program for multi-problem young adults: Study protocol for a randomized controlled trial",
abstract = "Background: Effective interventions for young adults with severe, multiple problems - such as psychosocial and psychiatric problems, delinquency, unemployment and substance use - are scarce but urgently needed in order to support an adequate transition to adulthood. A multimodal day treatment program called {"}New Opportunities{"} (in Dutch: {"}De Nieuwe Kans{"}; DNK) was specifically developed to target multi-problem young adults in The Netherlands. The aim of this study protocol is to describe the design of a randomized controlled trial (RCT) in clinical practice to examine the effectiveness of DNK in comparison with care as usual (CAU). Methods/design: Multi-problem young adults in Rotterdam, The Netherlands, will be assigned randomly to DNK (expected N = 150) and CAU (expected N = 150). Primary outcome measures are recidivism and self-sufficiency. Secondary outcome measures include quality of life, attending school/work, psychological functioning, cognitive distortions and substance use. Participant and program characteristics will be examined as potential moderators of effectiveness. Additionally, cost-effectiveness will be measured. During 14 months, data from multiple resources will be collected at four time points. Discussion: This study is one of the first RCTs on the effectiveness of interventions developed for multi-problem young adults. The results will contribute to the currently scant knowledge about what works for various multi-problem young adults in their transition to adulthood. In addition, the study protocol will provide insight into implementing an RCT in a dynamic setting of clinical practice. Trial registration: Dutch Trial Register, identifier: NTR5163. Registered on 17 April 2015; retrospectively registered during the recruitment phase.",
keywords = "Care as usual, Clinical practice, Effectiveness, Multi-problem young adults, Multimodal day treatment, Randomized controlled trial, Recidivism, Self-sufficiency",
author = "Luijks, {Marie Jolette A.} and Floor Bevaart and Josjan Zijlmans and {van Duin}, Laura and Reshmi Marhe and Doreleijers, {Theo A.H.} and Henning Tiemeier and Asscher, {Jessica J.} and Arne Popma",
year = "2017",
month = "5",
day = "19",
doi = "10.1186/s13063-017-1950-3",
language = "English",
volume = "18",
journal = "Trials",
issn = "1745-6215",
publisher = "BioMed Central",
number = "1",

}

A multimodal day treatment program for multi-problem young adults : Study protocol for a randomized controlled trial. / Luijks, Marie Jolette A.; Bevaart, Floor; Zijlmans, Josjan; van Duin, Laura; Marhe, Reshmi; Doreleijers, Theo A.H.; Tiemeier, Henning; Asscher, Jessica J.; Popma, Arne.

In: Trials, Vol. 18, No. 1, 225, 19.05.2017.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - A multimodal day treatment program for multi-problem young adults

T2 - Study protocol for a randomized controlled trial

AU - Luijks, Marie Jolette A.

AU - Bevaart, Floor

AU - Zijlmans, Josjan

AU - van Duin, Laura

AU - Marhe, Reshmi

AU - Doreleijers, Theo A.H.

AU - Tiemeier, Henning

AU - Asscher, Jessica J.

AU - Popma, Arne

PY - 2017/5/19

Y1 - 2017/5/19

N2 - Background: Effective interventions for young adults with severe, multiple problems - such as psychosocial and psychiatric problems, delinquency, unemployment and substance use - are scarce but urgently needed in order to support an adequate transition to adulthood. A multimodal day treatment program called "New Opportunities" (in Dutch: "De Nieuwe Kans"; DNK) was specifically developed to target multi-problem young adults in The Netherlands. The aim of this study protocol is to describe the design of a randomized controlled trial (RCT) in clinical practice to examine the effectiveness of DNK in comparison with care as usual (CAU). Methods/design: Multi-problem young adults in Rotterdam, The Netherlands, will be assigned randomly to DNK (expected N = 150) and CAU (expected N = 150). Primary outcome measures are recidivism and self-sufficiency. Secondary outcome measures include quality of life, attending school/work, psychological functioning, cognitive distortions and substance use. Participant and program characteristics will be examined as potential moderators of effectiveness. Additionally, cost-effectiveness will be measured. During 14 months, data from multiple resources will be collected at four time points. Discussion: This study is one of the first RCTs on the effectiveness of interventions developed for multi-problem young adults. The results will contribute to the currently scant knowledge about what works for various multi-problem young adults in their transition to adulthood. In addition, the study protocol will provide insight into implementing an RCT in a dynamic setting of clinical practice. Trial registration: Dutch Trial Register, identifier: NTR5163. Registered on 17 April 2015; retrospectively registered during the recruitment phase.

AB - Background: Effective interventions for young adults with severe, multiple problems - such as psychosocial and psychiatric problems, delinquency, unemployment and substance use - are scarce but urgently needed in order to support an adequate transition to adulthood. A multimodal day treatment program called "New Opportunities" (in Dutch: "De Nieuwe Kans"; DNK) was specifically developed to target multi-problem young adults in The Netherlands. The aim of this study protocol is to describe the design of a randomized controlled trial (RCT) in clinical practice to examine the effectiveness of DNK in comparison with care as usual (CAU). Methods/design: Multi-problem young adults in Rotterdam, The Netherlands, will be assigned randomly to DNK (expected N = 150) and CAU (expected N = 150). Primary outcome measures are recidivism and self-sufficiency. Secondary outcome measures include quality of life, attending school/work, psychological functioning, cognitive distortions and substance use. Participant and program characteristics will be examined as potential moderators of effectiveness. Additionally, cost-effectiveness will be measured. During 14 months, data from multiple resources will be collected at four time points. Discussion: This study is one of the first RCTs on the effectiveness of interventions developed for multi-problem young adults. The results will contribute to the currently scant knowledge about what works for various multi-problem young adults in their transition to adulthood. In addition, the study protocol will provide insight into implementing an RCT in a dynamic setting of clinical practice. Trial registration: Dutch Trial Register, identifier: NTR5163. Registered on 17 April 2015; retrospectively registered during the recruitment phase.

KW - Care as usual

KW - Clinical practice

KW - Effectiveness

KW - Multi-problem young adults

KW - Multimodal day treatment

KW - Randomized controlled trial

KW - Recidivism

KW - Self-sufficiency

UR - http://www.scopus.com/inward/record.url?scp=85019345662&partnerID=8YFLogxK

U2 - 10.1186/s13063-017-1950-3

DO - 10.1186/s13063-017-1950-3

M3 - Article

VL - 18

JO - Trials

JF - Trials

SN - 1745-6215

IS - 1

M1 - 225

ER -