A new approach to neuroimaging with magnetoencephalography

Arjan Hillebrand, Krish D Singh, Ian E Holliday, Paul Lawrence Furlong, Gareth R Barnes

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

We discuss the application of beamforming techniques to the field of magnetoencephalography (MEG). We argue that beamformers have given us an insight into the dynamics of oscillatory changes across the cortex not explored previously with traditional analysis techniques that rely on averaged evoked responses. We review several experiments that have used beamformers, with special emphasis on those in which the results have been compared to those observed in functional magnetic resonance imaging (fMRI) and on those studying induced phenomena. We suggest that the success of the beamformer technique, despite the assumption that there are no linear interactions between the mesoscopic local field potentials across distinct cortical areas, may tell us something of the balance between functional integration and segregation in the human brain. What is more, MEG beamformer analysis facilitates the study of these complex interactions within cortical networks that are involved in both sensory-motor and cognitive processes.

Original languageEnglish
Pages (from-to)199-211
Number of pages13
JournalHuman Brain Mapping
Volume25
Issue number2
DOIs
Publication statusPublished - Jun 2005
Externally publishedYes

Cite this

Hillebrand, A., Singh, K. D., Holliday, I. E., Furlong, P. L., & Barnes, G. R. (2005). A new approach to neuroimaging with magnetoencephalography. Human Brain Mapping, 25(2), 199-211. https://doi.org/10.1002/hbm.20102