A practical cytological approach to the diagnosis of breast-implant associated anaplastic large cell lymphoma

Ellis Barbé, Mintsje de Boer, Daphne de Jong

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

The role of cytopathology in malignant lymphoma is largely restricted to primary screening in patients with lymphadenopathy of unknown causes and evaluation of relapse and transformation during follow-up of patients with known and fully classified malignant lymphoma. Few lymphoma diagnoses fully rely on cytology, although breast-implant associated anaplastic large cell lymphoma is currently the centre of clinical attention. Due to the major attention both in the medical and lay media for the recently substantiated high lymphoma risk in women with breast implants, cytopathology departments now frequently receive seroma fluid aspirates with this specific differential diagnostic consideration. In this review, we discuss clinico-pathological aspects of breast-implant associated anaplastic large cell lymphoma from a cytological point of view and provide guidelines for the processing of aspirates in daily practice and strategies for diagnostic work-up of seroma fluids.
Original languageEnglish
JournalCytopathology
DOIs
Publication statusPublished - 2019

Cite this

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title = "A practical cytological approach to the diagnosis of breast-implant associated anaplastic large cell lymphoma",
abstract = "The role of cytopathology in malignant lymphoma is largely restricted to primary screening in patients with lymphadenopathy of unknown causes and evaluation of relapse and transformation during follow-up of patients with known and fully classified malignant lymphoma. Few lymphoma diagnoses fully rely on cytology, although breast-implant associated anaplastic large cell lymphoma is currently the centre of clinical attention. Due to the major attention both in the medical and lay media for the recently substantiated high lymphoma risk in women with breast implants, cytopathology departments now frequently receive seroma fluid aspirates with this specific differential diagnostic consideration. In this review, we discuss clinico-pathological aspects of breast-implant associated anaplastic large cell lymphoma from a cytological point of view and provide guidelines for the processing of aspirates in daily practice and strategies for diagnostic work-up of seroma fluids.",
author = "Ellis Barb{\'e} and {de Boer}, Mintsje and {de Jong}, Daphne",
year = "2019",
doi = "10.1111/cyt.12678",
language = "English",
journal = "CANCER CYTOPATHOLOGY",
issn = "1934-662X",
publisher = "Wiley-Blackwell",

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A practical cytological approach to the diagnosis of breast-implant associated anaplastic large cell lymphoma. / Barbé, Ellis; de Boer, Mintsje; de Jong, Daphne.

In: Cytopathology, 2019.

Research output: Contribution to journalReview articleAcademicpeer-review

TY - JOUR

T1 - A practical cytological approach to the diagnosis of breast-implant associated anaplastic large cell lymphoma

AU - Barbé, Ellis

AU - de Boer, Mintsje

AU - de Jong, Daphne

PY - 2019

Y1 - 2019

N2 - The role of cytopathology in malignant lymphoma is largely restricted to primary screening in patients with lymphadenopathy of unknown causes and evaluation of relapse and transformation during follow-up of patients with known and fully classified malignant lymphoma. Few lymphoma diagnoses fully rely on cytology, although breast-implant associated anaplastic large cell lymphoma is currently the centre of clinical attention. Due to the major attention both in the medical and lay media for the recently substantiated high lymphoma risk in women with breast implants, cytopathology departments now frequently receive seroma fluid aspirates with this specific differential diagnostic consideration. In this review, we discuss clinico-pathological aspects of breast-implant associated anaplastic large cell lymphoma from a cytological point of view and provide guidelines for the processing of aspirates in daily practice and strategies for diagnostic work-up of seroma fluids.

AB - The role of cytopathology in malignant lymphoma is largely restricted to primary screening in patients with lymphadenopathy of unknown causes and evaluation of relapse and transformation during follow-up of patients with known and fully classified malignant lymphoma. Few lymphoma diagnoses fully rely on cytology, although breast-implant associated anaplastic large cell lymphoma is currently the centre of clinical attention. Due to the major attention both in the medical and lay media for the recently substantiated high lymphoma risk in women with breast implants, cytopathology departments now frequently receive seroma fluid aspirates with this specific differential diagnostic consideration. In this review, we discuss clinico-pathological aspects of breast-implant associated anaplastic large cell lymphoma from a cytological point of view and provide guidelines for the processing of aspirates in daily practice and strategies for diagnostic work-up of seroma fluids.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060952992&origin=inward

UR - https://www.ncbi.nlm.nih.gov/pubmed/30628128

U2 - 10.1111/cyt.12678

DO - 10.1111/cyt.12678

M3 - Review article

JO - CANCER CYTOPATHOLOGY

JF - CANCER CYTOPATHOLOGY

SN - 1934-662X

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