A Primer on Interstitial Lung Disease and Thoracic Radiation

International Association for the Study of Lung Cancer Advanced Radiation Technology Committee

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Interstitial lung disease (ILD) is a term used to describe a heterogeneous group of lung disorders with characteristic clinical and imaging features. Patients with ILD are at an increased risk of developing NSCLC, which is frequently medically comorbid, often precluding operative management. In this scenario, radiotherapy (RT) is generally recommended; however, ILD is known to increase the risk of RT-related toxicity. Recommendations for treatment with appropriately individualized risks and benefits are thus dependent on integration of patient-, ILD-, and cancer-specific factors. We aim to provide an overview of ILD for the thoracic oncologist, an assessment of risk of thoracic RT in patients with ILD, and evidence-based recommendations for treatment in a variety of clinical scenarios.

Original languageEnglish
Pages (from-to)902-913
Number of pages12
JournalJournal of Thoracic Oncology
Volume15
Issue number6
Early online date24 Feb 2020
DOIs
Publication statusPublished - Jun 2020

Cite this