A space-occupying lesion of the skull base, masked by nasopharyngeal lymphatic tissue hypertrophy and causing cranial nerve dysfunction in an HIV-infected patient

H J J van der Vliet, M H J van Oers, L J Schot, C B L Majoie, J T M van der Meer

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Patients infected with HIV are at increased risk of developing lymphoma. The lymphomas often involve extranodal sites and +/-90% are of B-cell phenotype. We describe an HIV-infected patient with unilateral multiple cranial nerve dysfunction, most likely as a result of a nasopharyngeal B-cell non-Hodgkin's lymphoma in which early histologic confirmation of the diagnosis was delayed by the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy. It is of practical importance to recognize non-Hodgkin's lymphoma as a cause of cranial nerve dysfunction and to be aware of the possibility and the implications of the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy in HIV-infected patients.

Original languageEnglish
Pages (from-to)164-6
Number of pages3
JournalAnnals of Hematology
Volume81
Issue number3
DOIs
Publication statusPublished - Mar 2002

Cite this

@article{b1477ccd84664f30a98400b9fc799e63,
title = "A space-occupying lesion of the skull base, masked by nasopharyngeal lymphatic tissue hypertrophy and causing cranial nerve dysfunction in an HIV-infected patient",
abstract = "Patients infected with HIV are at increased risk of developing lymphoma. The lymphomas often involve extranodal sites and +/-90{\%} are of B-cell phenotype. We describe an HIV-infected patient with unilateral multiple cranial nerve dysfunction, most likely as a result of a nasopharyngeal B-cell non-Hodgkin's lymphoma in which early histologic confirmation of the diagnosis was delayed by the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy. It is of practical importance to recognize non-Hodgkin's lymphoma as a cause of cranial nerve dysfunction and to be aware of the possibility and the implications of the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy in HIV-infected patients.",
keywords = "Cranial Nerve Diseases/etiology, Fatal Outcome, Female, HIV Infections/complications, Humans, Lymphoma, Non-Hodgkin/complications, Magnetic Resonance Imaging, Middle Aged, Nasopharyngeal Neoplasms/complications, Skull Base Neoplasms/complications",
author = "{van der Vliet}, {H J J} and {van Oers}, {M H J} and Schot, {L J} and Majoie, {C B L} and {van der Meer}, {J T M}",
year = "2002",
month = "3",
doi = "10.1007/s00277-002-0428-9",
language = "English",
volume = "81",
pages = "164--6",
journal = "Annals of Hematology",
issn = "0939-5555",
publisher = "Springer Verlag",
number = "3",

}

A space-occupying lesion of the skull base, masked by nasopharyngeal lymphatic tissue hypertrophy and causing cranial nerve dysfunction in an HIV-infected patient. / van der Vliet, H J J; van Oers, M H J; Schot, L J; Majoie, C B L; van der Meer, J T M.

In: Annals of Hematology, Vol. 81, No. 3, 03.2002, p. 164-6.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - A space-occupying lesion of the skull base, masked by nasopharyngeal lymphatic tissue hypertrophy and causing cranial nerve dysfunction in an HIV-infected patient

AU - van der Vliet, H J J

AU - van Oers, M H J

AU - Schot, L J

AU - Majoie, C B L

AU - van der Meer, J T M

PY - 2002/3

Y1 - 2002/3

N2 - Patients infected with HIV are at increased risk of developing lymphoma. The lymphomas often involve extranodal sites and +/-90% are of B-cell phenotype. We describe an HIV-infected patient with unilateral multiple cranial nerve dysfunction, most likely as a result of a nasopharyngeal B-cell non-Hodgkin's lymphoma in which early histologic confirmation of the diagnosis was delayed by the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy. It is of practical importance to recognize non-Hodgkin's lymphoma as a cause of cranial nerve dysfunction and to be aware of the possibility and the implications of the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy in HIV-infected patients.

AB - Patients infected with HIV are at increased risk of developing lymphoma. The lymphomas often involve extranodal sites and +/-90% are of B-cell phenotype. We describe an HIV-infected patient with unilateral multiple cranial nerve dysfunction, most likely as a result of a nasopharyngeal B-cell non-Hodgkin's lymphoma in which early histologic confirmation of the diagnosis was delayed by the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy. It is of practical importance to recognize non-Hodgkin's lymphoma as a cause of cranial nerve dysfunction and to be aware of the possibility and the implications of the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy in HIV-infected patients.

KW - Cranial Nerve Diseases/etiology

KW - Fatal Outcome

KW - Female

KW - HIV Infections/complications

KW - Humans

KW - Lymphoma, Non-Hodgkin/complications

KW - Magnetic Resonance Imaging

KW - Middle Aged

KW - Nasopharyngeal Neoplasms/complications

KW - Skull Base Neoplasms/complications

U2 - 10.1007/s00277-002-0428-9

DO - 10.1007/s00277-002-0428-9

M3 - Article

VL - 81

SP - 164

EP - 166

JO - Annals of Hematology

JF - Annals of Hematology

SN - 0939-5555

IS - 3

ER -