A tumefactive demyelinating lesion in a person with MS after five years of fingolimod

L. Jeung; L. M.G. Smits; E. L.J. Hoogervorst; B. W. van Oosten; S. T.F.M. Frequin

doi:10.1016/j.msard.2020.101978

A tumefactive demyelinating lesion in a person with MS after five years of fingolimod

L. Jeung, L. M.G. Smits, E. L.J. Hoogervorst, B. W. van Oosten, S. T.F.M. Frequin

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A 38-year-old man with relapsing remitting multiple sclerosis (RRMS) developed a tumefactive demyelinating lesion (TDL) after being clinically and radiologically stable on fingolimod for the last five years. TDLs in MS tend to occur early on in the disease and are uncommon in longstanding MS. Compared to other immune modifying drugs used in MS, there is a relatively high and still increasing number of reports describing the development of TDL under treatment with fingolimod, suggesting a causal relation.

Original language	English
Article number	101978
Journal	Multiple Sclerosis and Related Disorders
Volume	40
DOIs	https://doi.org/10.1016/j.msard.2020.101978
Publication status	Published - 1 May 2020

Cite this

Jeung, L., Smits, L. M. G., Hoogervorst, E. L. J., van Oosten, B. W., & Frequin, S. T. F. M. (2020). A tumefactive demyelinating lesion in a person with MS after five years of fingolimod. Multiple Sclerosis and Related Disorders, 40, [101978]. https://doi.org/10.1016/j.msard.2020.101978

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10.1016/j.msard.2020.101978

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