Acquired encephaloceles and epilepsy in osteopetrosis

E. S. Mandl*, D. R. Buis, J. J. Heimans, S. M. Peerdeman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Osteopetrosis is a condition in which there is a defect in bone resorption by osteoclasts. With thickening of the skull and skull base, the cranial capacity becomes compromised and skull foramina gradually occlude, resulting in a wide range of neurological symptoms and signs. We present a case of autosomal dominant osteopetrosis with temporal lobe epilepsy and nasal obstruction due to acquired bifrontal encephaloceles associated with a decreased intracranial capacity. Neurosurgical reconstruction of the frontal skull base alleviated the symptoms of epilepsy and nasal obstruction.

Original languageEnglish
Pages (from-to)79-81
Number of pages3
JournalActa Neurochirurgica
Issue number1
Publication statusPublished - Jan 2007

Cite this