All SNPs are not created equal: Genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

A.J. Schork, W.K. Thompson, P. Pham, A. Torkamani, J.C. Roddey, P.F. Sullivan, J. Kelsoe, M.C. O'Donovan, H. Furberg, D. Absher, A. Agudo, P. Almgren, D. Ardissino, T.L. Assimes, S. Bandinelli, L. Barzan, V. Bencko, S. Benhamou, E.J. Benjamin, L. BernardinelliJ. Bis, M. Boehnke, E. Boerwinkle, D.I. Boomsma, P. Brennan, C. Canova, X. Castellsagué, S. Chanock, D.I. Chasman, D.I. Conway, J. Dackor, E.J.C. de Geus, J. Duan, R. Elosua, B. Everett, E. Fabianova, L. Ferrucci, L. Foretova, S.P. Fortmann, N. Franceschini, T.M. Frayling, C. Furberg, P.V. Gejman, L. Groop, F. Gu, J. Guralnik, S.E. Hankinson, T. Haritunians, C. Healy, A. Hofman, I. Holcátová, D.J. Hunter, S.J. Hwang, J.P.A. Ioannidis, C. Iribarren, A.U. Jackson, V. Janout, J. Kaprio, Y. Kim, K. Kjaerheim, J.W. Knowles, P. Kraft, C. Ladenvall, P. Lagiou, M. Lanthrop, C. Lerman, D.F. Levinson, D. Levy, M.D. Li, D.Y. Lin, E.H. Lips, J. Lissowska, R.B. Lowry, G. Lucas, T.V. Macfarlane, H.H.M. Maes, P.M. Mannucci, D. Mates, F. Mauri, J.A. McGovern, J.D. McKay, B. McKnight, O. Melander, P.A. Merlini, Y. Milaneschi, K.L. Mohlke, C.J. O'Donnell, G. Pare, B.W.J.H. Penninx, J.R.B. Perry, D. Posthuma, S.R. Preis, B. Psaty, T. Quertermous, V.S. Ramachandran, L. Richiardi, P.M. Ridker, J. Rose, P. Rudnai, V. Salomaa, A.R. Sanders, S.M. Schwartz, J. Shi, J.H. Smit, H.M. Stringham, N. Szeszenia-Dabrowska, T. Tanaka, K. Taylor, E.E. Thacker, L. Thornton, H. Tiemeier, J. Tuomilehto, A.G. Uitterlinden, C.M. van Duijn, J.M. Vink, N. Vogelzangs, B.F. Voight, S. Walter, G. Willemsen, D. Zaridze, A. Znaor, H. Akil, A. Anjorin, L. Backlund, J.A. Badner, J.D. Barchas, T. Barrett, N. Bass, M. Bauer, F. Bellivier, S.E. Bergen, W. Berrettini, D. Blackwood, C.S. Bloss, G. Breen, R. Breuer, W.E. Bunner, M. Burmeister, W. F. Byerley, S. Caesar, K. Chambert, S. Cichon, D. St Clair, D.A. Collier, A. Corvin, W.H. Coryell, N. Craddock, D.W. Craig, M. Daly, R. Day, F. Degenhardt, S. Djurovic, F. Dudbridge, H.J. Edenberg, A. Elkin, B. Etain, A.E. Farmer, M.A. Ferreira, I. Ferrier, M. Flickinger, T. Foroud, J. Frank, C. Fraser, L. Frisén, E.S. Gershon, M. Gill, K. Gordon-Smith, E.K. Green, T.A. Greenwood, D. Grozeva, W. Guan, H. Gurling, O. Gustafsson, M.L. Hamshere, M. Hautzinger, S. Herms, M. Hipolito, P.A. Holmans, C. M. Hultman, S. Jamain, E.G. Jones, I. Jones, L. Jones, R. Kandaswamy, J.L. Kennedy, G. K. Kirov, D.L. Koller, P. Kwan, M. Landén, N. Langstrom, M. Lathrop, J. Lawrence, W.B. Lawson, M. Leboyer, P.H. Lee, J. Li, P. Lichtenstein, D. Lin, C. Liu, F.W. Lohoff, S. Lucae, P.B. Mahon, W. Maier, N.G. Martin, M. Mattheisen, K. Matthews, M. Mattingsdal, K.A. McGhee, P. McGuffin, M.G. McInnis, A. McIntosh, R. McKinney, A.W. McLean, F.J. McMahon, A. McQuillin, S. Meier, I. Melle, F. Meng, P.B. Mitchell, G.W. Montgomery, J. Moran, G. Morken, D.W. Morris, V. Moskvina, P. Muglia, T.W. Mühleisen, W.J. Muir, B. Müller-Myhsok, R.M. Myers, C.M. Nievergelt, I. Nikolov, V.L. Nimgaonkar, M.M. Nöthen, J.I. Nurnberger, E.A. Nwulia, C. O'Dushlaine, U. Osby, H. Óskarsson, M.J. Owen, H. Petursson, B.S. Pickard, P. Porgeirsson, J.B. Potash, P. Propping, S.M. Purcell, E. Quinn, S. Raychaudhuri, J. Rice, M. Rietschel, D. Ruderfer, M. Schalling, A.F. Schatzberg, W.A. Scheftner, P.R. Schofield, T.G. Schulze, J. Schumacher, M.M. Schwarz, E. Scolnick, L.J. Scott, P.D. Shilling, E. Sigurdsson, P. Sklar, E.N. Smith, H. Stefansson, K. Stefansson, M Steffens, S. Steinberg, J. Strauss, J. Strohmaier, S. Szelinger, R.C. Thompson, F. Tozzi, J. Treutlein, J.B. Vincent, S.J. Watson, T.F. Wienker, R. Williamson, S.H. Witt, A. Wright, W. Xu, A.H. Young, P.P. Zandi, P. Zhang, S. Zöllner, I. Agartz, M. Albus, M. Alexander, R. L. Amdur, F. Amin, I. Bitter, D.W. Black, A.D. Børglum, M.A. Brown, R. Bruggeman, N.G. Buccola, W. Cahn, R.M. Cantor, V.J. Carr, S. V. Catts, K. Choudhury, C. R. Cloninger, P. Cormican, P. A. Danoy, S. Datta, M. DeHert, D. Demontis, D. Dikeos, P. Donnelly, G. Donohoe, L. Duong, S. Dwyer, A. Fanous, A. Fink-Jensen, R. Freedman, N.B. Freimer, M. Friedl, L. Georgieva, I. Giegling, B. Glenthoj, S. Godard, V. Golimbet, L. de Haan, M. Hansen, T. Hansen, A.M. Hartmann, F. A. Henskens, D. M. Hougaard, A. Ingason, A. V. Jablensky, K.D. Jakobsen, M. Jay, E.G. Jönsson, G. Jürgens, R.S. Kahn, M.C. Keller, K.S. Kendler, G. Kenis, E. Kenny, H. Konnerth, B. Konte, L. Krabbendam, R. Krasucki, V. K. Lasseter, C. Laurent, T. Lencz, F. B. Lerer, K. Y. Liang, J. A. Lieberman, D.H. Linszen, J. Lönnqvist, C. M. Loughland, A. W. Maclean, B.S. Maher, A.K. Malhotra, J. Mallet, P. Malloy, J. J. McGrath, D. E. McLean, P. T. Michie, V. Milanova, O. Mors, P.B. Mortensen, B. J. Mowry, I. Myin-Germeys, B. Neale, D. A. Nertney, G. Nestadt, J. Nielsen, M. Nordentoft, N. Norton, F. O'Neill, A. Olincy, L. Olsen, R.A. Ophoff, T. F. Orntoft, J. van Os, C. Pantelis, G. Papadimitriou, C.N. Pato, L. Peltonen, B. Pickard, O.P. Pietilainen, J. Pimm, A. E. Pulver, V. Puri, D. Quested, H.B. Rasmussen, J.M. Rethelyi, R. Ribble, B.P. Riley, L. Rossin, M. Ruggeri, D. Rujescu, U. Schall, S. G. Schwab, R.J. Scott, J.M. Silverman, C. C. Spencer, A. Strange, E. Strengman, T.S. Stroup, J. Suvisaari, L. Terenius, S. Thirumalai, S. Timm, D. Toncheva, S. Tosato, E.J. van den Oord, J. Veldink, P.M. Visscher, D. Walsh, A. G. Wang, T. Werge, D. Wiersma, D. B. Wildenauer, H.J. Williams, N.M. Williams, R. van Winkel, B. Wormley, S. Zammit, N.J. Schork, O.A. Andreassen, A.M. Dale

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article numbere1003449
Pages (from-to)e1003449
JournalPLoS Genetics
Volume9
Issue number4
DOIs
Publication statusPublished - 2013

Cite this

Schork, A. J., Thompson, W. K., Pham, P., Torkamani, A., Roddey, J. C., Sullivan, P. F., ... Dale, A. M. (2013). All SNPs are not created equal: Genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genetics, 9(4), e1003449. [e1003449]. https://doi.org/10.1371/journal.pgen.1003449