TY - JOUR
T1 - An EAPCI expert consensus document on ischaemia with non-obstructive coronary arteries in collaboration with european society of cardiology working group on coronary pathophysiology & microcirculation endorsed by coronary vasomotor disorders international study group
AU - Kunadian, Vijay
AU - Chieffo, Alaide
AU - Camici, Paolo G.
AU - Berry, Colin
AU - Escaned, Javier
AU - Maas, Angela H. E. M.
AU - Prescott, Eva
AU - Karam, Nicole
AU - Appelman, Yolande
AU - Fraccaro, Chiara
AU - Buchanan, Gill Louise
AU - Manzo-Silberman, Stephane
AU - Al-Lamee, Rasha
AU - Regar, Evelyn
AU - Lansky, Alexandra
AU - Abbott, J. Dawn
AU - Badimon, Lina
AU - Duncker, Dirk J.
AU - Mehran, Roxana
AU - Capodanno, Davide
AU - Baumbach, Andreas
PY - 2021
Y1 - 2021
N2 - This consensus document, a summary of the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI), appraises the importance of ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% of patients undergoing invasive angiography do not have obstructive coronary artery disease, more common in women than in men, and a large proportion have INOCA as a cause of their symptoms. INOCA patients present with a wide spectrum of symptoms and signs that are often misdiagnosed as non-cardiac leading to under-diagnosis/investigation and under-treatment. INOCA can result from heterogeneous mechanism including coronary vasospasm and microvascular dysfunction and is not a benign condition. Compared to asymptomatic individuals, INOCA is associated with increased incidence of cardiovascular events, repeated hospital admissions, as well as impaired quality of life and associated increased health care costs. This consensus document provides a definition of INOCA and guidance to the community on the diagnostic approach and management of INOCA based on existing evidence from research and best available clinical practice; noting gaps in knowledge and potential areas for further investigation.
AB - This consensus document, a summary of the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI), appraises the importance of ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% of patients undergoing invasive angiography do not have obstructive coronary artery disease, more common in women than in men, and a large proportion have INOCA as a cause of their symptoms. INOCA patients present with a wide spectrum of symptoms and signs that are often misdiagnosed as non-cardiac leading to under-diagnosis/investigation and under-treatment. INOCA can result from heterogeneous mechanism including coronary vasospasm and microvascular dysfunction and is not a benign condition. Compared to asymptomatic individuals, INOCA is associated with increased incidence of cardiovascular events, repeated hospital admissions, as well as impaired quality of life and associated increased health care costs. This consensus document provides a definition of INOCA and guidance to the community on the diagnostic approach and management of INOCA based on existing evidence from research and best available clinical practice; noting gaps in knowledge and potential areas for further investigation.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85100279843&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/32624456
U2 - 10.4244/EIJY20M07_01
DO - 10.4244/EIJY20M07_01
M3 - Review article
C2 - 32624456
VL - 16
SP - 1049
EP - 1069
JO - EuroIntervention
JF - EuroIntervention
SN - 1774-024X
IS - 13
ER -