Antineoplastic Drug Contamination on the Outside of Prepared Infusion Bags

Oscar Breukels, Toon van der Gronde, Kathleen Simons-Sanders, Mirjam Crul

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Eight Dutch hospital pharmacies took wipe samples of prepared infusion bags containing 5 fluorouracil just before distribution to the wards. The samples were tested with high-performance liquid chromatography and triple quadrupole mass spectroscopy. The limit of detection was 10 ng per swipe. None of the 146 samples had a detectable amount of 5-fluorouracil. The outside of infusion bags containing antineoplastic drugs prepared in these eight Dutch hospital pharmacies were not contaminated and, therefore, were not a risk factor with regard to exposure of hospital workers to antineoplastic drugs.
Original languageEnglish
Pages (from-to)345-349
JournalInternational journal of pharmaceutical compounding
Volume22
Issue number4
Publication statusPublished - 2018

Cite this

Breukels, Oscar ; van der Gronde, Toon ; Simons-Sanders, Kathleen ; Crul, Mirjam. / Antineoplastic Drug Contamination on the Outside of Prepared Infusion Bags. In: International journal of pharmaceutical compounding. 2018 ; Vol. 22, No. 4. pp. 345-349.
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Antineoplastic Drug Contamination on the Outside of Prepared Infusion Bags. / Breukels, Oscar; van der Gronde, Toon; Simons-Sanders, Kathleen; Crul, Mirjam.

In: International journal of pharmaceutical compounding, Vol. 22, No. 4, 2018, p. 345-349.

Research output: Contribution to journalArticleAcademicpeer-review

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