TY - JOUR
T1 - Association between lifestyle factors and quality- adjusted life years in the EPIC-NL cohort
AU - Fransen, Heidi P.
AU - May, Anne M.
AU - Beulens, Joline W.J.
AU - Struijk, Ellen A.
AU - De Wit, G. Ardine
AU - Boer, Jolanda M.A.
AU - Onland-Moret, N. Charlotte
AU - Hoekstra, Jeljer
AU - Der Schouw, Yvonne T.Van
AU - Bueno-De-mesquita, H. Bas
AU - Peeters, Petra H.M.
PY - 2014/11
Y1 - 2014/11
N2 - The aim of our study was to relate four modifiable lifestyle factors (smoking status, body mass index, physical activity and diet) to health expectancy, using quality-adjusted life years (QALYs) in a prospective cohort study. Data of the prospective EPIC-NL study were used, including 33,066 healthy men and women aged 20-70 years at baseline (1993-7), followed until 31-12-2007 for occurrence of disease and death. Smoking status, body mass index, physical activity and adherence to a Mediterranean-style diet (excluding alcohol) were investigated separately and combined into a healthy lifestyle score, ranging from 0 to 4. QALYs were used as summary measure of healthy life expectancy, combining a person's life expectancy with a weight for quality of life when having a chronic disease. For lifestyle factors analyzed separately the number of years living longer in good health varied from 0.12 year to 0.84 year, after adjusting for covariates. A combination of the four lifestyle factors was positively associated with higher QALYs (P-trend <0.0001). A healthy lifestyle score of 4 compared to a score of 0 was associated with almost a 2 years longer life in good health (1.75 QALYs [95% CI 1.37, 2.14]).
AB - The aim of our study was to relate four modifiable lifestyle factors (smoking status, body mass index, physical activity and diet) to health expectancy, using quality-adjusted life years (QALYs) in a prospective cohort study. Data of the prospective EPIC-NL study were used, including 33,066 healthy men and women aged 20-70 years at baseline (1993-7), followed until 31-12-2007 for occurrence of disease and death. Smoking status, body mass index, physical activity and adherence to a Mediterranean-style diet (excluding alcohol) were investigated separately and combined into a healthy lifestyle score, ranging from 0 to 4. QALYs were used as summary measure of healthy life expectancy, combining a person's life expectancy with a weight for quality of life when having a chronic disease. For lifestyle factors analyzed separately the number of years living longer in good health varied from 0.12 year to 0.84 year, after adjusting for covariates. A combination of the four lifestyle factors was positively associated with higher QALYs (P-trend <0.0001). A healthy lifestyle score of 4 compared to a score of 0 was associated with almost a 2 years longer life in good health (1.75 QALYs [95% CI 1.37, 2.14]).
UR - http://www.scopus.com/inward/record.url?scp=84930671038&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0111480
DO - 10.1371/journal.pone.0111480
M3 - Article
C2 - 25369457
AN - SCOPUS:84930671038
VL - 9
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 11
M1 - e111480
ER -