Abstract
OBJECTIVE: To determine whether there is an association between osteoarthritis (OA) and incident social isolation using data from the European Project on OSteoArthritis (EPOSA) study. DESIGN: Prospective, observational study with 12 to 18 months of follow-up. SETTING: Community dwelling. PARTICIPANTS: Older people living in six European countries. MEASUREMENTS: Social isolation was assessed using the Lubben Social Network Scale and the Maastricht Social Participation Profile. Clinical OA of the hip, knee, and hand was assessed according to American College of Rheumatology criteria. Demographic characteristics, including age, sex, multijoint pain, and medical comorbidities, were assessed. RESULTS: Of the 1967 individuals with complete baseline and follow-up data, 382 (19%) were socially isolated and 1585 were nonsocially isolated at baseline; of these individuals, 222 (13.9%) experienced social isolation during follow-up. Using logistic regression analyses, after adjustment for age, sex, and country, four factors were significantly associated with incident social isolation: clinical OA, cognitive impairment, depression, and worse walking time. Compared to those without OA at any site or with only hand OA, clinical OA of the hip and/or knee, combined or not with hand OA, led to a 1.47 times increased risk of social isolation (95% confidence interval = 1.03-2.09). CONCLUSION: Clinical OA, present in one or two sites of the hip and knee, or in two or three sites of the hip, knee, and hand, increased the risk of social isolation, adjusting for cognitive impairment and depression and worse walking times. Clinicians should be aware that individuals with OA may be at greater risk of social isolation. J Am Geriatr Soc 68:87–95, 2019.
Original language | English |
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Pages (from-to) | 87-95 |
Number of pages | 9 |
Journal | Journal of the American Geriatrics Society |
Volume | 68 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jan 2020 |
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Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study. / Siviero, Paola; Veronese, Nicola; Smith, Toby et al.
In: Journal of the American Geriatrics Society, Vol. 68, No. 1, 01.01.2020, p. 87-95.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study
AU - Siviero, Paola
AU - Veronese, Nicola
AU - Smith, Toby
AU - Stubbs, Brendon
AU - Limongi, Federica
AU - Zambon, Sabina
AU - Dennison, Elaine M.
AU - Edwards, Mark
AU - Cooper, Cyrus
AU - Timmermans, Erik J.
AU - van Schoor, Natasja M.
AU - van der Pas, Suzan
AU - Schaap, Laura A.
AU - Denkinger, Michael D.
AU - Peter, Richard
AU - Herbolsheimer, Florian
AU - Otero, Ángel
AU - Castell, Maria Victoria
AU - Pedersen, Nancy L.
AU - Deeg, Dorly J. H.
AU - Maggi, Stefania
AU - EPOSA Research Group
N1 - Funding Information: The corresponding author, Siviero, affirms that she has listed everyone who contributed significantly to the work and has obtained written consent from all contributors who are not authors and are named in this section. Appreciation is expressed to Linda Inverso Moretti for assistance in editing the manuscript. Financial Disclosure: The study was supported by a noncommercial private funder. The Indicators for Monitoring COPD [Chronic Obstructive Pulmonary Disease] and Asthma?Activity and Function in the Elderly in Ulm study was supported by the European Union (No. 2005121) and the Ministry of Science, Baden-W?rttemberg. The Italian cohort study is part of the National Research Council Project on Aging. The Longitudinal Aging Study Amsterdam is financially supported by The Netherlands Ministry of Health Welfare and Sports, Directorate of Long-Term Care. The Pe?agrande study was partially supported by the National Fund for Health Research (Fondo de Investigaciones en Salud) of Spain (project Nos. FIS PI 05/1898, FIS RETICEF RD06/0013/1013, and FIS PS09/02143). The Swedish Twin Registry is supported in part by the Swedish Ministry of Higher Education. The Hertfordshire Cohort Study is funded by the Medical Research Council of Great Britain, Arthritis Research UK, the British Heart Foundation, and the International Osteoporosis Foundation. Smith and Cooper are supported by the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre. The views expressed are those of these author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health. Conflicts of Interest: The authors have no conflicts. Author Contributions: Siviero has full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Smith, Stubbs, Zambon, Dennison, Edwards, Cooper, van Schoor, van der Pas, Schaap, Denkinger, Peter, Otero, Castell, Pedersen, Deeg, and Maggi. Acquisition of data: Siviero, Limongi, Zambon, Cooper, Dennison, Edwards, Timmermans, van der Pas, Schaap, van Schoor, Denkinger, Peter, Herbolsheimer, Otero, Castell, Pedersen, Deeg, and Maggi. Analysis and interpretation of data: Siviero, Veronese, Smith, Stubbs, Limongi, Dennison, Edwards, Cooper, Timmermans, van Schoor, van der Pas, Schaap, Denkinger, Peter, Herbolsheimer, Castell, Pedersen, Deeg, and Maggi. Preparation of manuscript: All the authors contributed to the drafting and critical revision of the manuscript, and all the authors have approved the final manuscript. Sponsor's Role: The sponsor had no role in the study design; the collection, analysis, and interpretation of the data; the writing of the report; and the decision to submit the article for publication. Funding Information: Financial Disclosure: The study was supported by a noncommercial private funder. The Indicators for Monitoring COPD [Chronic Obstructive Pulmonary Disease] and Asthma–Activity and Function in the Elderly in Ulm study was supported by the European Union (No. 2005121) and the Ministry of Science, Baden‐Württemberg. The Italian cohort study is part of the National Research Council Project on Aging. The Longitudinal Aging Study Amsterdam is financially supported by The Netherlands Ministry of Health Welfare and Sports, Directorate of Long‐Term Care. The Peñagrande study was partially supported by the National Fund for Health Research (Fondo de Investigaciones en Salud) of Spain (project Nos. FIS PI 05/1898, FIS RETICEF RD06/0013/1013, and FIS PS09/02143). The Swedish Twin Registry is supported in part by the Swedish Ministry of Higher Education. The Hertfordshire Cohort Study is funded by the Medical Research Council of Great Britain, Arthritis Research UK, the British Heart Foundation, and the International Osteoporosis Foundation. Smith and Cooper are supported by the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre. The views expressed are those of these author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health. Publisher Copyright: © 2019 The American Geriatrics Society Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - OBJECTIVE: To determine whether there is an association between osteoarthritis (OA) and incident social isolation using data from the European Project on OSteoArthritis (EPOSA) study. DESIGN: Prospective, observational study with 12 to 18 months of follow-up. SETTING: Community dwelling. PARTICIPANTS: Older people living in six European countries. MEASUREMENTS: Social isolation was assessed using the Lubben Social Network Scale and the Maastricht Social Participation Profile. Clinical OA of the hip, knee, and hand was assessed according to American College of Rheumatology criteria. Demographic characteristics, including age, sex, multijoint pain, and medical comorbidities, were assessed. RESULTS: Of the 1967 individuals with complete baseline and follow-up data, 382 (19%) were socially isolated and 1585 were nonsocially isolated at baseline; of these individuals, 222 (13.9%) experienced social isolation during follow-up. Using logistic regression analyses, after adjustment for age, sex, and country, four factors were significantly associated with incident social isolation: clinical OA, cognitive impairment, depression, and worse walking time. Compared to those without OA at any site or with only hand OA, clinical OA of the hip and/or knee, combined or not with hand OA, led to a 1.47 times increased risk of social isolation (95% confidence interval = 1.03-2.09). CONCLUSION: Clinical OA, present in one or two sites of the hip and knee, or in two or three sites of the hip, knee, and hand, increased the risk of social isolation, adjusting for cognitive impairment and depression and worse walking times. Clinicians should be aware that individuals with OA may be at greater risk of social isolation. J Am Geriatr Soc 68:87–95, 2019.
AB - OBJECTIVE: To determine whether there is an association between osteoarthritis (OA) and incident social isolation using data from the European Project on OSteoArthritis (EPOSA) study. DESIGN: Prospective, observational study with 12 to 18 months of follow-up. SETTING: Community dwelling. PARTICIPANTS: Older people living in six European countries. MEASUREMENTS: Social isolation was assessed using the Lubben Social Network Scale and the Maastricht Social Participation Profile. Clinical OA of the hip, knee, and hand was assessed according to American College of Rheumatology criteria. Demographic characteristics, including age, sex, multijoint pain, and medical comorbidities, were assessed. RESULTS: Of the 1967 individuals with complete baseline and follow-up data, 382 (19%) were socially isolated and 1585 were nonsocially isolated at baseline; of these individuals, 222 (13.9%) experienced social isolation during follow-up. Using logistic regression analyses, after adjustment for age, sex, and country, four factors were significantly associated with incident social isolation: clinical OA, cognitive impairment, depression, and worse walking time. Compared to those without OA at any site or with only hand OA, clinical OA of the hip and/or knee, combined or not with hand OA, led to a 1.47 times increased risk of social isolation (95% confidence interval = 1.03-2.09). CONCLUSION: Clinical OA, present in one or two sites of the hip and knee, or in two or three sites of the hip, knee, and hand, increased the risk of social isolation, adjusting for cognitive impairment and depression and worse walking times. Clinicians should be aware that individuals with OA may be at greater risk of social isolation. J Am Geriatr Soc 68:87–95, 2019.
KW - EPOSA
KW - epidemiology
KW - osteoarthritis
KW - social isolation
UR - http://www.scopus.com/inward/record.url?scp=85073950452&partnerID=8YFLogxK
U2 - 10.1111/jgs.16159
DO - 10.1111/jgs.16159
M3 - Article
C2 - 31529624
VL - 68
SP - 87
EP - 95
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
SN - 0002-8614
IS - 1
ER -