Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study

Paola Siviero, Nicola Veronese, Toby Smith, Brendon Stubbs, Federica Limongi, Sabina Zambon, Elaine M. Dennison, Mark Edwards, Cyrus Cooper, Erik J. Timmermans, Natasja M. van Schoor, Suzan van der Pas, Laura A. Schaap, Michael D. Denkinger, Richard Peter, Florian Herbolsheimer, Ángel Otero, Maria Victoria Castell, Nancy L. Pedersen, Dorly J. H. Deeg & 2 others Stefania Maggi, EPOSA Research Group

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: To determine whether there is an association between osteoarthritis (OA) and incident social isolation using data from the European Project on OSteoArthritis (EPOSA) study. DESIGN: Prospective, observational study with 12 to 18 months of follow-up. SETTING: Community dwelling. PARTICIPANTS: Older people living in six European countries. MEASUREMENTS: Social isolation was assessed using the Lubben Social Network Scale and the Maastricht Social Participation Profile. Clinical OA of the hip, knee, and hand was assessed according to American College of Rheumatology criteria. Demographic characteristics, including age, sex, multijoint pain, and medical comorbidities, were assessed. RESULTS: Of the 1967 individuals with complete baseline and follow-up data, 382 (19%) were socially isolated and 1585 were nonsocially isolated at baseline; of these individuals, 222 (13.9%) experienced social isolation during follow-up. Using logistic regression analyses, after adjustment for age, sex, and country, four factors were significantly associated with incident social isolation: clinical OA, cognitive impairment, depression, and worse walking time. Compared to those without OA at any site or with only hand OA, clinical OA of the hip and/or knee, combined or not with hand OA, led to a 1.47 times increased risk of social isolation (95% confidence interval = 1.03-2.09). CONCLUSION: Clinical OA, present in one or two sites of the hip and knee, or in two or three sites of the hip, knee, and hand, increased the risk of social isolation, adjusting for cognitive impairment and depression and worse walking times. Clinicians should be aware that individuals with OA may be at greater risk of social isolation.
Original languageEnglish
JournalJournal of the American Geriatrics Society
DOIs
Publication statusPublished - 1 Jan 2019

Cite this

Siviero, P., Veronese, N., Smith, T., Stubbs, B., Limongi, F., Zambon, S., ... EPOSA Research Group (2019). Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study. Journal of the American Geriatrics Society. https://doi.org/10.1111/jgs.16159
Siviero, Paola ; Veronese, Nicola ; Smith, Toby ; Stubbs, Brendon ; Limongi, Federica ; Zambon, Sabina ; Dennison, Elaine M. ; Edwards, Mark ; Cooper, Cyrus ; Timmermans, Erik J. ; van Schoor, Natasja M. ; van der Pas, Suzan ; Schaap, Laura A. ; Denkinger, Michael D. ; Peter, Richard ; Herbolsheimer, Florian ; Otero, Ángel ; Castell, Maria Victoria ; Pedersen, Nancy L. ; Deeg, Dorly J. H. ; Maggi, Stefania ; EPOSA Research Group. / Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study. In: Journal of the American Geriatrics Society. 2019.
@article{288dd05ad79448bf84a2d96507823baf,
title = "Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study",
abstract = "OBJECTIVE: To determine whether there is an association between osteoarthritis (OA) and incident social isolation using data from the European Project on OSteoArthritis (EPOSA) study. DESIGN: Prospective, observational study with 12 to 18 months of follow-up. SETTING: Community dwelling. PARTICIPANTS: Older people living in six European countries. MEASUREMENTS: Social isolation was assessed using the Lubben Social Network Scale and the Maastricht Social Participation Profile. Clinical OA of the hip, knee, and hand was assessed according to American College of Rheumatology criteria. Demographic characteristics, including age, sex, multijoint pain, and medical comorbidities, were assessed. RESULTS: Of the 1967 individuals with complete baseline and follow-up data, 382 (19{\%}) were socially isolated and 1585 were nonsocially isolated at baseline; of these individuals, 222 (13.9{\%}) experienced social isolation during follow-up. Using logistic regression analyses, after adjustment for age, sex, and country, four factors were significantly associated with incident social isolation: clinical OA, cognitive impairment, depression, and worse walking time. Compared to those without OA at any site or with only hand OA, clinical OA of the hip and/or knee, combined or not with hand OA, led to a 1.47 times increased risk of social isolation (95{\%} confidence interval = 1.03-2.09). CONCLUSION: Clinical OA, present in one or two sites of the hip and knee, or in two or three sites of the hip, knee, and hand, increased the risk of social isolation, adjusting for cognitive impairment and depression and worse walking times. Clinicians should be aware that individuals with OA may be at greater risk of social isolation.",
author = "Paola Siviero and Nicola Veronese and Toby Smith and Brendon Stubbs and Federica Limongi and Sabina Zambon and Dennison, {Elaine M.} and Mark Edwards and Cyrus Cooper and Timmermans, {Erik J.} and {van Schoor}, {Natasja M.} and {van der Pas}, Suzan and Schaap, {Laura A.} and Denkinger, {Michael D.} and Richard Peter and Florian Herbolsheimer and {\'A}ngel Otero and Castell, {Maria Victoria} and Pedersen, {Nancy L.} and Deeg, {Dorly J. H.} and Stefania Maggi and {EPOSA Research Group}",
year = "2019",
month = "1",
day = "1",
doi = "10.1111/jgs.16159",
language = "English",
journal = "Journal of the American Geriatrics Society",
issn = "0002-8614",
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Siviero, P, Veronese, N, Smith, T, Stubbs, B, Limongi, F, Zambon, S, Dennison, EM, Edwards, M, Cooper, C, Timmermans, EJ, van Schoor, NM, van der Pas, S, Schaap, LA, Denkinger, MD, Peter, R, Herbolsheimer, F, Otero, Á, Castell, MV, Pedersen, NL, Deeg, DJH, Maggi, S & EPOSA Research Group 2019, 'Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study' Journal of the American Geriatrics Society. https://doi.org/10.1111/jgs.16159

Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study. / Siviero, Paola; Veronese, Nicola; Smith, Toby; Stubbs, Brendon; Limongi, Federica; Zambon, Sabina; Dennison, Elaine M.; Edwards, Mark; Cooper, Cyrus; Timmermans, Erik J.; van Schoor, Natasja M.; van der Pas, Suzan; Schaap, Laura A.; Denkinger, Michael D.; Peter, Richard; Herbolsheimer, Florian; Otero, Ángel; Castell, Maria Victoria; Pedersen, Nancy L.; Deeg, Dorly J. H.; Maggi, Stefania; EPOSA Research Group.

In: Journal of the American Geriatrics Society, 01.01.2019.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study

AU - Siviero, Paola

AU - Veronese, Nicola

AU - Smith, Toby

AU - Stubbs, Brendon

AU - Limongi, Federica

AU - Zambon, Sabina

AU - Dennison, Elaine M.

AU - Edwards, Mark

AU - Cooper, Cyrus

AU - Timmermans, Erik J.

AU - van Schoor, Natasja M.

AU - van der Pas, Suzan

AU - Schaap, Laura A.

AU - Denkinger, Michael D.

AU - Peter, Richard

AU - Herbolsheimer, Florian

AU - Otero, Ángel

AU - Castell, Maria Victoria

AU - Pedersen, Nancy L.

AU - Deeg, Dorly J. H.

AU - Maggi, Stefania

AU - EPOSA Research Group

PY - 2019/1/1

Y1 - 2019/1/1

N2 - OBJECTIVE: To determine whether there is an association between osteoarthritis (OA) and incident social isolation using data from the European Project on OSteoArthritis (EPOSA) study. DESIGN: Prospective, observational study with 12 to 18 months of follow-up. SETTING: Community dwelling. PARTICIPANTS: Older people living in six European countries. MEASUREMENTS: Social isolation was assessed using the Lubben Social Network Scale and the Maastricht Social Participation Profile. Clinical OA of the hip, knee, and hand was assessed according to American College of Rheumatology criteria. Demographic characteristics, including age, sex, multijoint pain, and medical comorbidities, were assessed. RESULTS: Of the 1967 individuals with complete baseline and follow-up data, 382 (19%) were socially isolated and 1585 were nonsocially isolated at baseline; of these individuals, 222 (13.9%) experienced social isolation during follow-up. Using logistic regression analyses, after adjustment for age, sex, and country, four factors were significantly associated with incident social isolation: clinical OA, cognitive impairment, depression, and worse walking time. Compared to those without OA at any site or with only hand OA, clinical OA of the hip and/or knee, combined or not with hand OA, led to a 1.47 times increased risk of social isolation (95% confidence interval = 1.03-2.09). CONCLUSION: Clinical OA, present in one or two sites of the hip and knee, or in two or three sites of the hip, knee, and hand, increased the risk of social isolation, adjusting for cognitive impairment and depression and worse walking times. Clinicians should be aware that individuals with OA may be at greater risk of social isolation.

AB - OBJECTIVE: To determine whether there is an association between osteoarthritis (OA) and incident social isolation using data from the European Project on OSteoArthritis (EPOSA) study. DESIGN: Prospective, observational study with 12 to 18 months of follow-up. SETTING: Community dwelling. PARTICIPANTS: Older people living in six European countries. MEASUREMENTS: Social isolation was assessed using the Lubben Social Network Scale and the Maastricht Social Participation Profile. Clinical OA of the hip, knee, and hand was assessed according to American College of Rheumatology criteria. Demographic characteristics, including age, sex, multijoint pain, and medical comorbidities, were assessed. RESULTS: Of the 1967 individuals with complete baseline and follow-up data, 382 (19%) were socially isolated and 1585 were nonsocially isolated at baseline; of these individuals, 222 (13.9%) experienced social isolation during follow-up. Using logistic regression analyses, after adjustment for age, sex, and country, four factors were significantly associated with incident social isolation: clinical OA, cognitive impairment, depression, and worse walking time. Compared to those without OA at any site or with only hand OA, clinical OA of the hip and/or knee, combined or not with hand OA, led to a 1.47 times increased risk of social isolation (95% confidence interval = 1.03-2.09). CONCLUSION: Clinical OA, present in one or two sites of the hip and knee, or in two or three sites of the hip, knee, and hand, increased the risk of social isolation, adjusting for cognitive impairment and depression and worse walking times. Clinicians should be aware that individuals with OA may be at greater risk of social isolation.

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UR - https://www.ncbi.nlm.nih.gov/pubmed/31529624

U2 - 10.1111/jgs.16159

DO - 10.1111/jgs.16159

M3 - Article

JO - Journal of the American Geriatrics Society

JF - Journal of the American Geriatrics Society

SN - 0002-8614

ER -