Author Correction: Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly (Nature Communications, (2020), 11, 1, (4038), 10.1038/s41467-020-17454-4)

Lu Wang, Zhen Li, David Sievert, Desirée E. C. Smith, Marisa I. Mendes, Dillon Y. Chen, Valentina Stanley, Shereen Ghosh, Yulu Wang, Majdi Kara, Ayca Dilruba Aslanger, Rasim O. Rosti, Henry Houlden, Gajja S. Salomons, Joseph G. Gleeson*

*Corresponding author for this work

Research output: Contribution to journalErratum/CorrigendumAcademicpeer-review


The original version of this Article omitted a reference to another publication which included overlapping genetic and MRI data for a research participant. This has been added as reference 59 at the end of the Discussion: ‘While this paper was under review, a separate paper appeared reporting that mutations in NARS1 associate with neurodevelopmental delay through either biallelic loss or dominant negative effects, impairing NARS1 enzyme activity. This article contained genetic data on family MIC-1433 which overlaps this study59.’ Accordingly, reference 59 has now been included in the References section as ‘Manole, A. et al. De novo and bi-allelic pathogenic variants in NARS1 cause neurodevelopmental delay due to toxic gain-of-function and partial loss-of-function effects. Am. J. Hum. Genet. 107(2), 311–324 (2020).’ In addition, the original version of this Article contained an error in Fig. 1A, where there was an error in the family depiction in generation 1 of pedigree MIC-1433; this has been revised to correctly depict the family. Figure 1D also contained MRI scans that had been previously published in Ref 59; this has been revised to include different and unpublished MRI scans from the same individual. (Figure presented.).
Original languageEnglish
Article number1192
JournalNature Communications
Issue number1
Publication statusPublished - 1 Dec 2021

Cite this