Bacterial meningitis caused by the use of ventricular or lumbar cerebrospinal fluid catheters

Rogier P. Schade*, Janke Schinkel, Leo G. Visser, Marc C. Van Dijk, Joan H.C. Voormolen, Ed J. Kuijper

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Object. In the present study the authors compared the incidence and risk factors for external drainage-related bacterial meningitis (ED-BM) by using ventricular and lumbar catheters. Methods. A cohort of 230 consecutive patients with ED was evaluated. Cerebrospinal fluid samples were obtained daily for microbiological culture, and ED-BM was defined based on culture results in combination with clinical symptoms. The incidence of ED-BM was 7% in lumbar and 15% in ventricular drains. Independent risk factors included site leakage, drain blockage, and most importantly duration of ED. Despite a higher infection rate, ventricular catheters did not have a significant higher risk of infection after correcting for duration of drainage. Conclusions. Analysis of data in the present study showed that the incidence of ED-associated death is low (0.45%) in patients who do not receive continuous antibiotic prophylaxis during ED.

Original languageEnglish
Pages (from-to)229-234
Number of pages6
JournalJournal of Neurosurgery
Volume102
Issue number2
DOIs
Publication statusPublished - 1 Feb 2005
Externally publishedYes

Cite this

Schade, R. P., Schinkel, J., Visser, L. G., Van Dijk, M. C., Voormolen, J. H. C., & Kuijper, E. J. (2005). Bacterial meningitis caused by the use of ventricular or lumbar cerebrospinal fluid catheters. Journal of Neurosurgery, 102(2), 229-234. https://doi.org/10.3171/jns.2005.102.2.0229