Ballonpulmonalisangioplastiek voor chronische trombo-embolische pulmonale hypertensie

Translated title of the contribution: Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension

G A de Waard, M C A M Melenhorst, M A H van Leeuwen, H J Bogaard, R J Lely, N van Royen

Research output: Contribution to journalArticleProfessional


Chronic thromboembolic pulmonary hypertension (CTEPH) is characterised by an elevated average blood pressure in the pulmonary artery (≥ 25 mmHg). This increase is secondary to fibrous organization of thromboembolic obstructions in the pulmonary arteries. CTEPH is associated with significant morbidity and mortality due to right-sided heart failure and ventilation-perfusion discrepancy. Therapy is aimed at normalising pulmonary artery pressure, and pulmonary endarterectomy is usually the treatment of first choice. When surgery is not possible because of peripheral disease localisation or comorbidity, percutaneous balloon pulmonary angioplasty (BPA) can be used. BPA is associated with improvements in functional status and haemodynamic profile. Initially procedural complications often occurred, but improvements in procedural technique have ensured that BPA is used increasingly worldwide. In this article, we discuss the history, procedural aspects and outcomes of BPA, and present our first experiences with BPA in a patient with CTEPH.

Translated title of the contributionBalloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension
Original languageDutch
Pages (from-to)A9807
JournalNederlands Tijdschrift voor Geneeskunde
Publication statusPublished - 2016

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