Behandeling van MS-gerelateerde vermoeidheid: recente inzichten

M de Gier; H Beckerman; Hans Knoop; V de Groot

Behandeling van MS-gerelateerde vermoeidheid: recente inzichten

Translated title of the contribution: Treatment of MS-related fatigue: recent insights

M de Gier^*, H Beckerman, Hans Knoop, V de Groot

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Fatigue is a common symptom in multiple sclerosis
(MS), and has a large impact on daily functioning of
patients. In the Netherlands, fatigue in MS is usually
treated in a multidisciplinary rehabilitation setting,
and often consists of physical training and energy
conservation management. In the Dutch MS guideline
(2012), amantadine and modafinil are suggested
as treatment options as well. In this paper, recent literature
on various treatments for MS-related fatigue
is discussed. It is concluded that multidisciplinary
rehabilitation treatment, aerobic training and energy
conservation management do not seem to be effective
treatments for MS-related fatigue. Evidence for
pharmacotherapy is still inconclusive; amantadine
might be effective. Cognitive behavioral therapy
(CBT) for MS-related fatigue does show positive
short-term effects. We present a study aimed at nationwide
implementation of CBT for fatigue and improving
long term outcome following treatment.

Translated title of the contribution	Treatment of MS-related fatigue: recent insights
Original language	Dutch
Pages (from-to)	236-41
Number of pages	6
Journal	Tijdschrift voor Neurologie & Neurochirurgie
Volume	121
Issue number	6
Publication status	Published - 18 Dec 2020

Cite this

@article{d464991ef35b442f8c4a5b654d0b76a7,

title = "Behandeling van MS-gerelateerde vermoeidheid: recente inzichten",

abstract = "Fatigue is a common symptom in multiple sclerosis(MS), and has a large impact on daily functioning ofpatients. In the Netherlands, fatigue in MS is usuallytreated in a multidisciplinary rehabilitation setting,and often consists of physical training and energyconservation management. In the Dutch MS guideline(2012), amantadine and modafinil are suggestedas treatment options as well. In this paper, recent literatureon various treatments for MS-related fatigueis discussed. It is concluded that multidisciplinaryrehabilitation treatment, aerobic training and energyconservation management do not seem to be effectivetreatments for MS-related fatigue. Evidence forpharmacotherapy is still inconclusive; amantadinemight be effective. Cognitive behavioral therapy(CBT) for MS-related fatigue does show positiveshort-term effects. We present a study aimed at nationwideimplementation of CBT for fatigue and improvinglong term outcome following treatment.",

author = "{de Gier}, M and H Beckerman and Hans Knoop and {de Groot}, V",

year = "2020",

month = dec,

day = "18",

language = "Dutch",

volume = "121",

pages = "236--41",

journal = "Tijdschrift voor Neurologie & Neurochirurgie",

issn = "1571-5930",

number = "6",

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TY - JOUR

T1 - Behandeling van MS-gerelateerde vermoeidheid: recente inzichten

AU - de Gier, M

AU - Beckerman, H

AU - Knoop, Hans

AU - de Groot, V

PY - 2020/12/18

Y1 - 2020/12/18

N2 - Fatigue is a common symptom in multiple sclerosis(MS), and has a large impact on daily functioning ofpatients. In the Netherlands, fatigue in MS is usuallytreated in a multidisciplinary rehabilitation setting,and often consists of physical training and energyconservation management. In the Dutch MS guideline(2012), amantadine and modafinil are suggestedas treatment options as well. In this paper, recent literatureon various treatments for MS-related fatigueis discussed. It is concluded that multidisciplinaryrehabilitation treatment, aerobic training and energyconservation management do not seem to be effectivetreatments for MS-related fatigue. Evidence forpharmacotherapy is still inconclusive; amantadinemight be effective. Cognitive behavioral therapy(CBT) for MS-related fatigue does show positiveshort-term effects. We present a study aimed at nationwideimplementation of CBT for fatigue and improvinglong term outcome following treatment.

AB - Fatigue is a common symptom in multiple sclerosis(MS), and has a large impact on daily functioning ofpatients. In the Netherlands, fatigue in MS is usuallytreated in a multidisciplinary rehabilitation setting,and often consists of physical training and energyconservation management. In the Dutch MS guideline(2012), amantadine and modafinil are suggestedas treatment options as well. In this paper, recent literatureon various treatments for MS-related fatigueis discussed. It is concluded that multidisciplinaryrehabilitation treatment, aerobic training and energyconservation management do not seem to be effectivetreatments for MS-related fatigue. Evidence forpharmacotherapy is still inconclusive; amantadinemight be effective. Cognitive behavioral therapy(CBT) for MS-related fatigue does show positiveshort-term effects. We present a study aimed at nationwideimplementation of CBT for fatigue and improvinglong term outcome following treatment.

M3 - Article

VL - 121

SP - 236

EP - 241

JO - Tijdschrift voor Neurologie & Neurochirurgie

JF - Tijdschrift voor Neurologie & Neurochirurgie

SN - 1571-5930

IS - 6

ER -