Blaassparende behandelingen bij blaaskanker: mogelijkheden en ontwikkelingen in de radiotherapie.

Maarten C. C. M. Hulshof, Bradley R. Pieters, Caro C. E. Koning

Research output: Contribution to journalReview articleProfessional


The standard treatment for muscle-invasive bladder cancer is surgical removal of the bladder and construction of a neobladder. Recently, important improvements have been made in the potential for bladder-conserving treatment using radiotherapy. External beam radiotherapy has undergone technological improvements, as a result of which it is possible to radiate the tumour more precisely while decreasing radiation to healthy tissue. Radiochemotherapy improves local recurrence-free and overall survival compared with radiotherapy alone. The results of this combined treatment are comparable with those of surgery. Additionally, Dutch radiotherapy departments have collected data in a national database of 1040 selected patients with confined bladder cancer. These patients were treated with external beam radiation, limited surgery and brachytherapy. The 5-year local recurrence-free survival was 75%. Bladder conserving treatment options for muscle-invasive bladder cancer should be discussed during the multidisciplinary meeting.
Original languageDutch
JournalNederlands Tijdschrift voor Geneeskunde
Issue number19
Publication statusPublished - 2013
Externally publishedYes

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