Breeding brains? Patients' and laymen's perspectives on cerebral organoids

Dolly R. Haselager, Sarah N. Boers, Karin R. Jongsma, Christiaan H. Vinkers, Marike L. Broekman, Annelien L. Bredenoord*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Aim: To explore the perspectives of patients and laymen with regard to the development, use and storage of cerebral organoids, in order to contribute to the ethical debate about this technology. Materials & methods: In depth semi-structured interviews with 28 patients and laymen were conducted. A qualitative thematic analysis was undertaken using a constant comparative method. Results: Three interrelated themes emerged from the empirical material: moral value; willingness to donate; and elements of good governance. Conclusion: Patients and laymen are most concerned about cerebral organoids potentially developing consciousness and potential misuse. They support the use of cerebral organoids under the conditions that donors are adequately informed and that there will be good governance. Perspectives of patients and laymen are helpful to enable responsible development and use of cerebral organoids in practice.

Original languageEnglish
Pages (from-to)2351-2360
Number of pages10
JournalRegenerative medicine
Volume15
Issue number12
DOIs
Publication statusPublished - Dec 2020

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