Following coronary revascularization, patients treated with coronary arteiy bypass graft surgery (CABG) have lower risk of major adverse cardiovascular events when compared with those treated with percutaneous coronaiy intervention (PCI). We compared changes in cardiovascular risk factors, such as psychological and cardiometabolic health indicators, among patients who completed cardiac rehabili-tation (CR) following CABG and PCI. Longitudinal records of 278 patients who completed an outpatient CR program following CABG or PCI were analyzed. We compared changes in anxiety and depression assessed by the Hospital Anxiety and Depression Scale (HADS); health-related quality of life (HR-QoL) measured by the Medical Outcomes Study Short Form-36 (SF-36); and indicators of cardiometabolic health (i.e., body mass, blood pressure, glucose, and lipid profiles) between CABG and PCI groups using analysis of covariance (ANCOVA). At baseline, patients treated with PCI (n=191) had superior physical function (i.e., physical functioning: 62.5±22.1 vs. 54.3±23.0 points, p=0.006; and role limitations due to physical health: 31.2±36.8 vs. 20.6±318 points, p=0.024) when compared with those treated with CABG (n=87). Following CR, patients treated with PCI showed significantly smaller improvements in depression (-0.4±3.1 vs.-1.3±2.7 points, p=0.036) and mental HR-QoL (mental component summary: 2.4±10.8 vs. 5.7±10.7 points, p=0.020) when compared with those treated with CABG. Novelty • Patients with coronary artery disease treated with PCI have smaller functional limitations but similar psychological health when compared with those treated with CABG at CR enrollment. • Patients participating in CR following PCI appear to achieve smaller psychological health benefits from CR when compared with those recovering from CABG.