Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer

Tesa M. Severson, Yongsoo Kim, Stacey E. P. Joosten, Karianne Schuurman, Petra van der Groep, Cathy B. Moelans, Natalie D. ter Hoeve, Quirine F. Manson, John W. Martens, Carolien H. M. van Deurzen, Ellis Barbe, Ingrid Hedenfalk, Peter Bult, Vincent T. H. B. M. Smit, Sabine C. Linn, Paul J. van Diest, Lodewyk Wessels, Wilbert Zwart

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Male breast cancer (MBC) is rare and largely hormonally driven. Here, the authors examine the action of steroid hormone receptors in male and female breast cancers and find gender selective hormone receptor action that associates with the survival of MBC patients.
Original languageEnglish
Article number482
JournalNature Communications
Volume9
Issue number1
DOIs
Publication statusPublished - 2018

Cite this

Severson, T. M., Kim, Y., Joosten, S. E. P., Schuurman, K., van der Groep, P., Moelans, C. B., ... Zwart, W. (2018). Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer. Nature Communications, 9(1), [482]. https://doi.org/10.1038/s41467-018-02856-2