Clinical Cardiogenetics: Second Edition

Hubert F. Baars*, Pieter A.F.M. Doevendans, Arjan C. Houweling, J. Peter van Tintelen

*Corresponding author for this work

Research output: Book/ReportBookAcademicpeer-review

Abstract

Clinical management and signs are the focus of this practical cardiogenetic reference for those who are involved in the care for cardiac patients with a genetic disease. With detailed discussion of the basic science of cardiogenetics in order to assist in the clinical understanding of the topic. The genetic causes of various cardiovascular diseases are explained in a concise clinical way that reinforces the current management doctrine in a practical manner. The authors will cover the principles of molecular genetics in general but also specific to cardiac diseases. They will discuss the etiology, pathogenesis, pathophysiology, clinical presentation, clinical diagnosis, molecular diagnosis and treatment of each cardiogenetic disease separately. Therapy advice, ICD indications, indications for and manner of further family investigation will all be covered, while each chapter will also contain take-home messages to reinforce the key points. The chapters reviewing the different diseases will each contain a table describing the genes involved in each. Each chapter will also contain specific illustrations, cumulatively giving a complete, practical review of each cardiogenetic disease separately. Special emphasis will be given to advice on how to diagnose and manage cardiogenetic diseases in clinical practice, which genes should be investigated and why, and the pros and cons of genetic testing. Guidelines for investigation in families with sudden cardiac death at young age will also be include.

Original languageEnglish
PublisherSpringer International Publishing Switzerland
Number of pages405
ISBN (Electronic)9783319442037
ISBN (Print)9783319442020
DOIs
Publication statusPublished - 30 Nov 2016

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