Medicatiebeoordelingen bij ouderen met polyfarmacie

Translated title of the contribution: Clinical medication reviews in elderly patients with polypharmacy: A cross-sectional study in Dutch community pharmacies

Sek Hung Chau*, Aaltje P.D. Jansen, Peter M. De Van Ven, Petra Hoogland, Petra J.M. Elders, Jacqueline G. Hugtenburg

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Objective To investigate the nature and prevalence of drug related problems (DRPs) in older patients with polypharmacy identified by community pharmacists in daily practice through means of a clinical medication review (CMR) and assess the implementation rate of proposed interventions to solve DRPs. Design A cross-sectional study Method We analysed the CMR data of 3,807 older patients (≥ 65 years) with polypharmacy (≥ 5 drugs) completed in January-August 2012. Using the "Service Apotheek Medicatie Review Tool" (SAMRT, Service Pharmacy Medication Review Tool), pharmacists in 258 community pharmacies registered the patients' year of birth, gender, dispensing data, DRPs, and proposed and implemented interventions. Results Pharmacists identified a median of two DRPs (interquartile range 1-4; mean 3.0) per patient. The DRP categories overtreatment (25.5 %) and undertreatment (15.9 %) were found to occur most frequently. On average, 46.2 % of the proposed interventions to address DRPs were implemented as proposed. In 22.4 % of cases the intervention differed from the Conclusion In daily practice, community pharmacists identified a mean of three DRPs in older patients with polypharmacy, a number comparable to that found in controlled studies. Over- or undertreatment caused nearly half of the identified DRPs. The majority (69.9%) of the proposed interventions led to an intervention for the patient.

Original languageDutch
Article numberD439
JournalNederlands Tijdschrift voor Geneeskunde
Issue number4
Publication statusPublished - 2017

Cite this

Chau, S. H., Jansen, A. P. D., De Van Ven, P. M., Hoogland, P., Elders, P. J. M., & Hugtenburg, J. G. (2017). Medicatiebeoordelingen bij ouderen met polyfarmacie. Nederlands Tijdschrift voor Geneeskunde, 161(4), [D439].