Clinical use of a waveguide hyperthermia system for superficial tumors with deep infiltration

H. P. Kok, G. van Stam, J. Sijbrands, A. Bakker, M. W. Kolff, G. van Tienhoven, M. C. C. M. Hulshof, J. Crezee

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

We have developed a new double waveguide system (AMC-2 system) for hyperthermia treatment (i.e heating tumor tissue to 40-43°C) of superficial tumors with deep infiltration. The system consists of two opposing rectangular 70 MHz rotatable waveguides. The aperture size of the bottom antenna is 20×34cm. The top antenna is interchangeable and antennas with an aperture size of 20×34cm, 15×34cm and 8.5×34cm can be selected. Clinical use of this system was demonstrated for a patient with a recurrent breast tumor. Four weekly hyperthermia sessions were applied in combination with a standard radiotherapy scheme. In order to gradually increase treatment complexity, in the first two sessions only one antenna was used and the last two sessions were performed with two antennas. Results show that appropriate phase steering can substantially improve tumor heating and thereby treatment quality. Clinical hyperthermia with this system was shown feasible.
Original languageEnglish
Title of host publicationEuropean Microwave Week 2017: "A Prime Year for a Prime Event", EuMW 2017 - Conference Proceedings; 47th European Microwave Conference, EuMC 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages868-871
Volume2017-January
ISBN (Electronic)9782874870477
DOIs
Publication statusPublished - 2017
Externally publishedYes
Event47th European Microwave Conference, EuMC 2017 - Nuremburg, Germany
Duration: 10 Oct 201712 Oct 2017

Publication series

NameEuropean Microwave Week 2017: "A Prime Year for a Prime Event", EuMW 2017 - Conference Proceedings; 47th European Microwave Conference, EuMC 2017

Conference

Conference47th European Microwave Conference, EuMC 2017
CountryGermany
CityNuremburg
Period10/10/201712/10/2017

Cite this

Kok, H. P., van Stam, G., Sijbrands, J., Bakker, A., Kolff, M. W., van Tienhoven, G., ... Crezee, J. (2017). Clinical use of a waveguide hyperthermia system for superficial tumors with deep infiltration. In European Microwave Week 2017: "A Prime Year for a Prime Event", EuMW 2017 - Conference Proceedings; 47th European Microwave Conference, EuMC 2017 (Vol. 2017-January, pp. 868-871). (European Microwave Week 2017: "A Prime Year for a Prime Event", EuMW 2017 - Conference Proceedings; 47th European Microwave Conference, EuMC 2017). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.23919/EuMC.2017.8230982