Cognitive mediation of panic reduction during an early intervention for panic

P. Meulenbeek, P. Spinhoven, H.F.E. Smit, A.J.L.M. van Balkom, P. Cuijpers

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objective:  This study investigated cognitive mediation of improvement in panic disorder (PD) symptomatology during and after an early intervention for panic symptoms in subthreshold and mild PD.

Method:  We executed a pragmatic, pre-post, two-group, multi-site, randomized trial of an early intervention for panic symptoms, based on cognitive-behavioural therapy, vs. a wait-list control group in a sample of 217 participants with subthreshold PD or mild PD.

Results:  First, two of the three subscales of the mediator variable Panic Appraisal Inventory (PAI-anticipation and PAI-coping) significantly mediated residual change in PD symptomatology on the PD Severity Scale-Self Report. Second, preintervention to postintervention PAI-anticipation and PAI-coping change scores significantly predicted postintervention to follow-up change in PD symptomatology after controlling for other change scores. However, the converse association was also significant.

Conclusion:  The results suggest that changes in cognitions may mediate changes in PD symptomatology and that the process of change is circular.
Original languageUndefined/Unknown
Pages (from-to)20-29
JournalActa Psychiatrica Scandinavica
Volume122
Issue number1
DOIs
Publication statusPublished - 2010

Cite this

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title = "Cognitive mediation of panic reduction during an early intervention for panic",
abstract = "Objective:  This study investigated cognitive mediation of improvement in panic disorder (PD) symptomatology during and after an early intervention for panic symptoms in subthreshold and mild PD.Method:  We executed a pragmatic, pre-post, two-group, multi-site, randomized trial of an early intervention for panic symptoms, based on cognitive-behavioural therapy, vs. a wait-list control group in a sample of 217 participants with subthreshold PD or mild PD.Results:  First, two of the three subscales of the mediator variable Panic Appraisal Inventory (PAI-anticipation and PAI-coping) significantly mediated residual change in PD symptomatology on the PD Severity Scale-Self Report. Second, preintervention to postintervention PAI-anticipation and PAI-coping change scores significantly predicted postintervention to follow-up change in PD symptomatology after controlling for other change scores. However, the converse association was also significant.Conclusion:  The results suggest that changes in cognitions may mediate changes in PD symptomatology and that the process of change is circular.",
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Cognitive mediation of panic reduction during an early intervention for panic. / Meulenbeek, P.; Spinhoven, P.; Smit, H.F.E.; van Balkom, A.J.L.M.; Cuijpers, P.

In: Acta Psychiatrica Scandinavica, Vol. 122, No. 1, 2010, p. 20-29.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - Cognitive mediation of panic reduction during an early intervention for panic

AU - Meulenbeek, P.

AU - Spinhoven, P.

AU - Smit, H.F.E.

AU - van Balkom, A.J.L.M.

AU - Cuijpers, P.

PY - 2010

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AB - Objective:  This study investigated cognitive mediation of improvement in panic disorder (PD) symptomatology during and after an early intervention for panic symptoms in subthreshold and mild PD.Method:  We executed a pragmatic, pre-post, two-group, multi-site, randomized trial of an early intervention for panic symptoms, based on cognitive-behavioural therapy, vs. a wait-list control group in a sample of 217 participants with subthreshold PD or mild PD.Results:  First, two of the three subscales of the mediator variable Panic Appraisal Inventory (PAI-anticipation and PAI-coping) significantly mediated residual change in PD symptomatology on the PD Severity Scale-Self Report. Second, preintervention to postintervention PAI-anticipation and PAI-coping change scores significantly predicted postintervention to follow-up change in PD symptomatology after controlling for other change scores. However, the converse association was also significant.Conclusion:  The results suggest that changes in cognitions may mediate changes in PD symptomatology and that the process of change is circular.

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