Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter

Anita Chandra; Fang Zhang; Kimberly C Gilmour; David Webster; Vincent Plagnol; Dinakantha S Kumararatne; Siobhan O Burns; Sergey Nejentsev; Adrian J Thrasher

doi:10.1016/j.jaci.2015.08.049

Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter

Anita Chandra, Fang Zhang, Kimberly C Gilmour, David Webster, Vincent Plagnol, Dinakantha S Kumararatne, Siobhan O Burns, Sergey Nejentsev, Adrian J Thrasher

Molecular cell biology and Immunology

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	940-2.e4
Journal	Journal of Allergy and Clinical Immunology
Volume	137
Issue number	3
DOIs	https://doi.org/10.1016/j.jaci.2015.08.049
Publication status	Published - Mar 2016

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10.1016/j.jaci.2015.08.049

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Chandra, A., Zhang, F., Gilmour, K. C., Webster, D., Plagnol, V., Kumararatne, D. S., ... Thrasher, A. J. (2016). Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter. Journal of Allergy and Clinical Immunology, 137(3), 940-2.e4. https://doi.org/10.1016/j.jaci.2015.08.049

Chandra, Anita ; Zhang, Fang ; Gilmour, Kimberly C ; Webster, David ; Plagnol, Vincent ; Kumararatne, Dinakantha S ; Burns, Siobhan O ; Nejentsev, Sergey ; Thrasher, Adrian J. / Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter. In: Journal of Allergy and Clinical Immunology. 2016 ; Vol. 137, No. 3. pp. 940-2.e4.

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title = "Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter",

keywords = "Adult, Binding Sites, Child, Preschool, Common Variable Immunodeficiency/diagnosis, Humans, Interleukin Receptor Common gamma Subunit/genetics, Killer Cells, Natural/metabolism, Lymphopenia/diagnosis, Male, Mutation, Promoter Regions, Genetic, Protein Binding, Proto-Oncogene Proteins c-ets/metabolism",

author = "Anita Chandra and Fang Zhang and Gilmour, {Kimberly C} and David Webster and Vincent Plagnol and Kumararatne, {Dinakantha S} and Burns, {Siobhan O} and Sergey Nejentsev and Thrasher, {Adrian J}",

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Chandra, A, Zhang, F, Gilmour, KC, Webster, D, Plagnol, V, Kumararatne, DS, Burns, SO, Nejentsev, S & Thrasher, AJ 2016, 'Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter', Journal of Allergy and Clinical Immunology, vol. 137, no. 3, pp. 940-2.e4. https://doi.org/10.1016/j.jaci.2015.08.049

Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter. / Chandra, Anita; Zhang, Fang; Gilmour, Kimberly C; Webster, David; Plagnol, Vincent; Kumararatne, Dinakantha S; Burns, Siobhan O; Nejentsev, Sergey; Thrasher, Adrian J.

In: Journal of Allergy and Clinical Immunology, Vol. 137, No. 3, 03.2016, p. 940-2.e4.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter

AU - Chandra, Anita

AU - Zhang, Fang

AU - Gilmour, Kimberly C

AU - Webster, David

AU - Plagnol, Vincent

AU - Kumararatne, Dinakantha S

AU - Burns, Siobhan O

AU - Nejentsev, Sergey

AU - Thrasher, Adrian J

PY - 2016/3

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KW - Adult

KW - Binding Sites

KW - Child, Preschool

KW - Common Variable Immunodeficiency/diagnosis

KW - Humans

KW - Interleukin Receptor Common gamma Subunit/genetics

KW - Killer Cells, Natural/metabolism

KW - Lymphopenia/diagnosis

KW - Male

KW - Mutation

KW - Promoter Regions, Genetic

KW - Protein Binding

KW - Proto-Oncogene Proteins c-ets/metabolism

U2 - 10.1016/j.jaci.2015.08.049

DO - 10.1016/j.jaci.2015.08.049

M3 - Article

C2 - 26525228

VL - 137

SP - 940-2.e4

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

SN - 0091-6749

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