Comparative diagnostic accuracy of dual-energy CT myocardial perfusion imaging by monochromatic energy versus material decomposition methods

Ibrahim Danad; Iksung Cho; Kimberly Elmore; Joshua Schulman-Marcus; Bríain Ó Hartaigh; Wijnand J Stuijfzand; Patricia Carrascosa; James K Min

doi:10.1016/j.clinimag.2017.11.002

Comparative diagnostic accuracy of dual-energy CT myocardial perfusion imaging by monochromatic energy versus material decomposition methods

Ibrahim Danad, Iksung Cho, Kimberly Elmore, Joshua Schulman-Marcus, Bríain Ó Hartaigh, Wijnand J Stuijfzand, Patricia Carrascosa, James K Min

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

PURPOSE: To compare the diagnostic value of monochromatic and material decomposition (MD) dual- energy computed tomography (DECT) imaging for the evaluation of ischemia.

METHODS: Patients with suspected coronary artery disease underwent rest-stress DECT and SPECT perfusion imaging. DECT images were reconstructed between 40 and 140keV and through MD of iodine/muscle.

RESULTS: MD and monochromatic imaging had a sensitivity, specificity, negative predictive, positive predictive value, and accuracy of 89%, 40%, 67%, 73% and 71%; and 91%, 67%, 67%, 91% and 86%, respectively (p=0.05).

CONCLUSION: DECT using monochromatic energy displayed a non-significantly higher diagnostic accuracy for myocardial ischemia as compared with DECT MD.

Original language	English
Pages (from-to)	1-4
Number of pages	4
Journal	Clinical imaging
Volume	50
DOIs	https://doi.org/10.1016/j.clinimag.2017.11.002
Publication status	Published - 11 Jul 2018

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10.1016/j.clinimag.2017.11.002

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title = "Comparative diagnostic accuracy of dual-energy CT myocardial perfusion imaging by monochromatic energy versus material decomposition methods",

abstract = "PURPOSE: To compare the diagnostic value of monochromatic and material decomposition (MD) dual- energy computed tomography (DECT) imaging for the evaluation of ischemia.METHODS: Patients with suspected coronary artery disease underwent rest-stress DECT and SPECT perfusion imaging. DECT images were reconstructed between 40 and 140keV and through MD of iodine/muscle.RESULTS: MD and monochromatic imaging had a sensitivity, specificity, negative predictive, positive predictive value, and accuracy of 89%, 40%, 67%, 73% and 71%; and 91%, 67%, 67%, 91% and 86%, respectively (p=0.05).CONCLUSION: DECT using monochromatic energy displayed a non-significantly higher diagnostic accuracy for myocardial ischemia as compared with DECT MD.",

keywords = "Journal Article",

author = "Ibrahim Danad and Iksung Cho and Kimberly Elmore and Joshua Schulman-Marcus and {{\'O} Hartaigh}, Br{\'i}ain and Stuijfzand, {Wijnand J} and Patricia Carrascosa and Min, {James K}",

note = "Published by Elsevier Inc.",

year = "2018",

month = jul,

day = "11",

doi = "10.1016/j.clinimag.2017.11.002",

language = "English",

volume = "50",

pages = "1--4",

journal = "Clinical imaging",

issn = "0899-7071",

publisher = "Elsevier Inc.",

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Comparative diagnostic accuracy of dual-energy CT myocardial perfusion imaging by monochromatic energy versus material decomposition methods. / Danad, Ibrahim; Cho, Iksung; Elmore, Kimberly; Schulman-Marcus, Joshua; Ó Hartaigh, Bríain; Stuijfzand, Wijnand J; Carrascosa, Patricia; Min, James K.

In: Clinical imaging, Vol. 50, 11.07.2018, p. 1-4.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Comparative diagnostic accuracy of dual-energy CT myocardial perfusion imaging by monochromatic energy versus material decomposition methods

AU - Danad, Ibrahim

AU - Cho, Iksung

AU - Elmore, Kimberly

AU - Schulman-Marcus, Joshua

AU - Ó Hartaigh, Bríain

AU - Stuijfzand, Wijnand J

AU - Carrascosa, Patricia

AU - Min, James K

N1 - Published by Elsevier Inc.

PY - 2018/7/11

Y1 - 2018/7/11

N2 - PURPOSE: To compare the diagnostic value of monochromatic and material decomposition (MD) dual- energy computed tomography (DECT) imaging for the evaluation of ischemia.METHODS: Patients with suspected coronary artery disease underwent rest-stress DECT and SPECT perfusion imaging. DECT images were reconstructed between 40 and 140keV and through MD of iodine/muscle.RESULTS: MD and monochromatic imaging had a sensitivity, specificity, negative predictive, positive predictive value, and accuracy of 89%, 40%, 67%, 73% and 71%; and 91%, 67%, 67%, 91% and 86%, respectively (p=0.05).CONCLUSION: DECT using monochromatic energy displayed a non-significantly higher diagnostic accuracy for myocardial ischemia as compared with DECT MD.

AB - PURPOSE: To compare the diagnostic value of monochromatic and material decomposition (MD) dual- energy computed tomography (DECT) imaging for the evaluation of ischemia.METHODS: Patients with suspected coronary artery disease underwent rest-stress DECT and SPECT perfusion imaging. DECT images were reconstructed between 40 and 140keV and through MD of iodine/muscle.RESULTS: MD and monochromatic imaging had a sensitivity, specificity, negative predictive, positive predictive value, and accuracy of 89%, 40%, 67%, 73% and 71%; and 91%, 67%, 67%, 91% and 86%, respectively (p=0.05).CONCLUSION: DECT using monochromatic energy displayed a non-significantly higher diagnostic accuracy for myocardial ischemia as compared with DECT MD.

KW - Journal Article

U2 - 10.1016/j.clinimag.2017.11.002

DO - 10.1016/j.clinimag.2017.11.002

M3 - Article

C2 - 29220708

VL - 50

SP - 1

EP - 4

JO - Clinical imaging

JF - Clinical imaging

SN - 0899-7071

ER -