Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Multi-Centre Study

Christine I. Harrington*, David Goldin, Christopher R. Lovell, Peter Van De Kerkhof, Cees Nieboer, Joar Austad, Lars Molin, Birgitta Wilson Clareus, Eva Rask-Pedersen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: Calcipotriol ointment is an effective treatment for psoriasis vulgaris. Although cream formulations have a less emollient effect they are often more acceptable to patients. Objective: To compare calcipotriol 50 μg/g in two different cream formulations with vehicle in patients with psoriasis vulgaris. Method: A randomised, double-blind, parallel group, multi-centre, comparison of cream A in which calcipotriol 50μg/g is dissolved, cream B in which calcipotriol 50 μg/g is suspended as fine particles and vehicle. A 2-week wash-out period was followed by 8 weeks double-blind treatment.

Original languageEnglish
Pages (from-to)152-158
Number of pages7
JournalJournal of the European Academy of Dermatology and Venereology
Volume6
Issue number2
DOIs
Publication statusPublished - 1 Jan 1996

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