Computed Tomography Observer Agreement in Staging Malignant Lymphoma

Antoinette de Jong, Thomas C Kwee, Henriëtte M E Quarles van Ufford, Frederik J A Beek, Lorentz G B A Quekel, John M H de Klerk, Josée M Zijlstra, Rob Fijnheer, Inge Ludwig, Marie José Kersten, Jaap Stoker, Rutger A J Nievelstein

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OBJECTIVE: To determine pretreatment computed tomography observer agreement in patients with newly diagnosed lymphoma.

METHODS: Forty-nine computed tomography scans were reviewed by 3 experienced radiologists, with each scan assessed twice by 1 observer. Predefined nodal and extranodal regions were assessed, and Ann Arbor stages were assigned. K-statistics were defined as poor (κ < 0.2), fair (κ > 0.2 to κ ≤ 0.4), moderate (κ > 0.4 to κ ≤ 0.6), substantial (κ > 0.6 to κ ≤ 0.8), and almost perfect (κ > 0.8 to κ ≤ 1).

RESULTS: Nodal interobserver agreement varied from 0.09 for infraclavicular involvement to 0.95 for para-iliac involvement; intraobserver agreement was substantial to almost perfect, except for infraclavicular nodes. Extranodal interobserver agreement varied from 0.56 to 0.88; intraobserver agreement was substantial to almost perfect. Ann Arbor stage interobserver agreement varied from 0.57 to 0.69; intraobserver agreement was substantial.

CONCLUSION: Computed tomography observer agreement in staging malignant lymphoma appears to be suboptimal.

Original languageEnglish
Pages (from-to)261-265
Number of pages5
JournalJournal of Computer Assisted Tomography
Issue number2
Publication statusPublished - 26 Nov 2015

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