TY - JOUR
T1 - Conduction disorders in bradyasystolic out-of-hospital cardiac arrest
AU - Hulleman, Michiel
AU - Mes, Hanne
AU - Blom, Marieke T.
AU - Koster, Rudolph W.
N1 - Funding Information:
MH is supported by a grant from the Netherlands Heart Foundation (grant no. 2013T034 ). The study funder was not involved in study design, data-collection, analysis, interpretation or in writing of the manuscript.
Publisher Copyright:
© 2016 The Author(s)
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Aims Bradyasystolic heart rhythms are often recorded in out-of-hospital cardiac arrest (OHCA). Atrioventricular (AV) conduction disorders might lead to OHCA, but the prevalence of AV-conduction disorders and other bradyasystolic rhythms in OHCA is unknown. These patients might benefit from pre-hospital pacing. We aimed to determine the prevalence of different types of bradyasystolic heart rhythms in OHCA, including third degree AV-block, and document survival rates. Methods We used data from the ARREST-registry of OHCA in the Netherlands. Patients with bradyasystolic OHCA in 2006–2012 were included. ECGs were classified according to the presence of P-waves and QRS complexes in five rhythm groups. Differences in survival to discharge in relation to resuscitation characteristics, rhythm and pacing were tested using Chi-Square test and multivariate regression analysis. Results We included 2333 patients with a bradyasystolic rhythm; 371 patients (16%) presented with a third degree AV-block. In total 45 patients (1.9%, 95%-CI 1.4–2.5%) survived. A third degree AV-block (adjusted OR 0.86, 95%-CI 0.38–1.96) or pacing (adjusted OR 0.89, 95%-CI 0.21–3.78) was not associated with survival. Pacing was initiated in 110 patients (4.7%), after a long delay (median 18.7 min). The strongest association with survival was found for the presence of a bradycardia (vs. asystole) (adjusted OR 4.20, 95%-CI 1.79–9.83), bystander witnessed (OR 4.13, 95%-CI 1.45–11.8) and EMS witnessed collapse (OR 5.18, 95%-CI 2.77–9.67). Conclusion In bradyasystolic OHCA, 16% of all patients present with third degree AV-block, but survival for these and other bradyasystolic patients remains poor. Pacing is seldom initiated, often delayed, and rarely beneficial.
AB - Aims Bradyasystolic heart rhythms are often recorded in out-of-hospital cardiac arrest (OHCA). Atrioventricular (AV) conduction disorders might lead to OHCA, but the prevalence of AV-conduction disorders and other bradyasystolic rhythms in OHCA is unknown. These patients might benefit from pre-hospital pacing. We aimed to determine the prevalence of different types of bradyasystolic heart rhythms in OHCA, including third degree AV-block, and document survival rates. Methods We used data from the ARREST-registry of OHCA in the Netherlands. Patients with bradyasystolic OHCA in 2006–2012 were included. ECGs were classified according to the presence of P-waves and QRS complexes in five rhythm groups. Differences in survival to discharge in relation to resuscitation characteristics, rhythm and pacing were tested using Chi-Square test and multivariate regression analysis. Results We included 2333 patients with a bradyasystolic rhythm; 371 patients (16%) presented with a third degree AV-block. In total 45 patients (1.9%, 95%-CI 1.4–2.5%) survived. A third degree AV-block (adjusted OR 0.86, 95%-CI 0.38–1.96) or pacing (adjusted OR 0.89, 95%-CI 0.21–3.78) was not associated with survival. Pacing was initiated in 110 patients (4.7%), after a long delay (median 18.7 min). The strongest association with survival was found for the presence of a bradycardia (vs. asystole) (adjusted OR 4.20, 95%-CI 1.79–9.83), bystander witnessed (OR 4.13, 95%-CI 1.45–11.8) and EMS witnessed collapse (OR 5.18, 95%-CI 2.77–9.67). Conclusion In bradyasystolic OHCA, 16% of all patients present with third degree AV-block, but survival for these and other bradyasystolic patients remains poor. Pacing is seldom initiated, often delayed, and rarely beneficial.
KW - Asystole
KW - AV-conduction disorders
KW - Bradyasystole
KW - Bradycardia
KW - Cardiac arrest
KW - Cardiopulmonary resuscitation
KW - Pulseless electrical activity
KW - Transcutaneous pacing
UR - http://www.scopus.com/inward/record.url?scp=84979645687&partnerID=8YFLogxK
U2 - 10.1016/j.resuscitation.2016.06.033
DO - 10.1016/j.resuscitation.2016.06.033
M3 - Article
C2 - 27422306
AN - SCOPUS:84979645687
SN - 0300-9572
VL - 106
SP - 113
EP - 119
JO - Resuscitation
JF - Resuscitation
ER -