Congenitale trombocytopenie bij volwassenen

Translated title of the contribution: Congenital thrombocytopenia in adults

Annette van Zweeden, Pieter Bot, Yves Smets, Wim Terpstra

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Thrombocytopenia in adult patients is usually acquired. Important causes are medication, pregnancy, infections and auto-immune disorders. Here we present 2 patients, a 32-year-old and a 45-year-old man, in whom congenital thrombocytopenia was discovered in adulthood, caused by a mutation in the gene for Wiskott-Aldrich syndrome. This congenital thrombocytopenia appears in different forms. Indications for the disorder are chronic thrombocytopenia, a family history and additional clinical signs such as eczema and renal insufficiency. Measurement of the thrombocyte size is a helpful tool in the diagnosis. Recognition of congenital thrombocytopenia can have important clinical consequences.

Original languageDutch
Pages (from-to)A2634
JournalNederlands Tijdschrift voor Geneeskunde
Volume155
Publication statusPublished - 2011

Cite this

van Zweeden, A., Bot, P., Smets, Y., & Terpstra, W. (2011). Congenitale trombocytopenie bij volwassenen. Nederlands Tijdschrift voor Geneeskunde, 155, A2634.