Consequences of diagnosing a tumor predisposition syndrome in children with cancer: A literature review

Floor A. M. Postema, Saskia M. J. Hopman, Raoul C. Hennekam, Johannes H. M. Merks

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Up to 8.5% of children with cancer have a genetic cause for their cancer: a tumor predisposition syndrome (TPS). Diagnosing a TPS is of great importance, as it may have major consequences for clinical care. Patients with TPSs require specific monitoring and management. We present an overview of the cancer-related and noncancer-related consequences for the 36 most common TPSs.
Original languageEnglish
Article numbere26718
JournalPediatric Blood and Cancer
Volume65
Issue number1
DOIs
Publication statusPublished - 2018
Externally publishedYes

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