Construct validity of the pediatric Rome III criteria

Miguel Saps, Diana X Nichols-Vinueza, Stijn Mintjens, Cenk K Pusatcioglu, Carlos A Velasco-Benítez

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVES: Functional gastrointestinal disorders (FGIDs) are common. The diagnosis of FGIDs is based on the Rome criteria, a symptom-based diagnostic classification established by expert consensus. There is little evidence of validity for the pediatric Rome III criteria. The construct validity of the criteria, an overarching term that incorporates other forms of validity, has never been assessed. We assessed the construct validity of the Rome III criteria.

METHODS: Children from 2 schools in Colombia completed the Questionnaire on Pediatric Gastrointestinal Symptoms at baseline and weekly questionnaires of somatic symptoms and disability for 8 weeks (presence and intensity of gastrointestinal symptoms, nongastrointestinal symptoms, impact on daily activities). A total of 255 children completed at least 6 weekly surveys (2041 surveys).

RESULTS: At baseline, 27.8% children were diagnosed as having an FGID. Prevalence of nausea (Δ 7.8%, 95% confidence interval [CI] 4.46-11.14), constipation (Δ 4.39%, 95% CI 1.79-6.99), diarrhea (Δ 6.69%, 95% CI 3.25-10.13), headache (Δ 7.4%, 95% CI 3.51-11.09), chest pain (Δ 9.04%, 95% CI 5.20-12.88), and limb pain (Δ 4.07%, 95% CI 1.76-6.37) and intensity of nausea (Δ 0.23, 95% CI 0.127-0.333), diarrhea (Δ 0.30, 95% CI 0.211-0.389), abdominal pain (Δ 0.18, 95% CI 0.069-0.291), headache (Δ 0.17, 95% CI 0.091-0.249), and limb pain (Δ 0.30, 95% CI 0.084-0.516) were higher in children with FGIDs (P < 0.001). Children with FGIDs had greater interference with daily activities (P < 0.001).

CONCLUSIONS: Children with a Rome III diagnosis had significantly more gastrointestinal and nongastrointestinal complaints, and greater intensity of symptoms and disability than children without an FGID diagnosis. The study suggests that the Rome III pediatric criteria have adequate construct validity.

Original languageEnglish
Pages (from-to)577-81
Number of pages5
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume59
Issue number5
DOIs
Publication statusPublished - Nov 2014

Cite this

Saps, Miguel ; Nichols-Vinueza, Diana X ; Mintjens, Stijn ; Pusatcioglu, Cenk K ; Velasco-Benítez, Carlos A. / Construct validity of the pediatric Rome III criteria. In: Journal of Pediatric Gastroenterology and Nutrition. 2014 ; Vol. 59, No. 5. pp. 577-81.
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title = "Construct validity of the pediatric Rome III criteria",
abstract = "OBJECTIVES: Functional gastrointestinal disorders (FGIDs) are common. The diagnosis of FGIDs is based on the Rome criteria, a symptom-based diagnostic classification established by expert consensus. There is little evidence of validity for the pediatric Rome III criteria. The construct validity of the criteria, an overarching term that incorporates other forms of validity, has never been assessed. We assessed the construct validity of the Rome III criteria.METHODS: Children from 2 schools in Colombia completed the Questionnaire on Pediatric Gastrointestinal Symptoms at baseline and weekly questionnaires of somatic symptoms and disability for 8 weeks (presence and intensity of gastrointestinal symptoms, nongastrointestinal symptoms, impact on daily activities). A total of 255 children completed at least 6 weekly surveys (2041 surveys).RESULTS: At baseline, 27.8{\%} children were diagnosed as having an FGID. Prevalence of nausea (Δ 7.8{\%}, 95{\%} confidence interval [CI] 4.46-11.14), constipation (Δ 4.39{\%}, 95{\%} CI 1.79-6.99), diarrhea (Δ 6.69{\%}, 95{\%} CI 3.25-10.13), headache (Δ 7.4{\%}, 95{\%} CI 3.51-11.09), chest pain (Δ 9.04{\%}, 95{\%} CI 5.20-12.88), and limb pain (Δ 4.07{\%}, 95{\%} CI 1.76-6.37) and intensity of nausea (Δ 0.23, 95{\%} CI 0.127-0.333), diarrhea (Δ 0.30, 95{\%} CI 0.211-0.389), abdominal pain (Δ 0.18, 95{\%} CI 0.069-0.291), headache (Δ 0.17, 95{\%} CI 0.091-0.249), and limb pain (Δ 0.30, 95{\%} CI 0.084-0.516) were higher in children with FGIDs (P < 0.001). Children with FGIDs had greater interference with daily activities (P < 0.001).CONCLUSIONS: Children with a Rome III diagnosis had significantly more gastrointestinal and nongastrointestinal complaints, and greater intensity of symptoms and disability than children without an FGID diagnosis. The study suggests that the Rome III pediatric criteria have adequate construct validity.",
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author = "Miguel Saps and Nichols-Vinueza, {Diana X} and Stijn Mintjens and Pusatcioglu, {Cenk K} and Velasco-Ben{\'i}tez, {Carlos A}",
year = "2014",
month = "11",
doi = "10.1097/MPG.0000000000000482",
language = "English",
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Saps, M, Nichols-Vinueza, DX, Mintjens, S, Pusatcioglu, CK & Velasco-Benítez, CA 2014, 'Construct validity of the pediatric Rome III criteria' Journal of Pediatric Gastroenterology and Nutrition, vol. 59, no. 5, pp. 577-81. https://doi.org/10.1097/MPG.0000000000000482

Construct validity of the pediatric Rome III criteria. / Saps, Miguel; Nichols-Vinueza, Diana X; Mintjens, Stijn; Pusatcioglu, Cenk K; Velasco-Benítez, Carlos A.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 59, No. 5, 11.2014, p. 577-81.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Construct validity of the pediatric Rome III criteria

AU - Saps, Miguel

AU - Nichols-Vinueza, Diana X

AU - Mintjens, Stijn

AU - Pusatcioglu, Cenk K

AU - Velasco-Benítez, Carlos A

PY - 2014/11

Y1 - 2014/11

N2 - OBJECTIVES: Functional gastrointestinal disorders (FGIDs) are common. The diagnosis of FGIDs is based on the Rome criteria, a symptom-based diagnostic classification established by expert consensus. There is little evidence of validity for the pediatric Rome III criteria. The construct validity of the criteria, an overarching term that incorporates other forms of validity, has never been assessed. We assessed the construct validity of the Rome III criteria.METHODS: Children from 2 schools in Colombia completed the Questionnaire on Pediatric Gastrointestinal Symptoms at baseline and weekly questionnaires of somatic symptoms and disability for 8 weeks (presence and intensity of gastrointestinal symptoms, nongastrointestinal symptoms, impact on daily activities). A total of 255 children completed at least 6 weekly surveys (2041 surveys).RESULTS: At baseline, 27.8% children were diagnosed as having an FGID. Prevalence of nausea (Δ 7.8%, 95% confidence interval [CI] 4.46-11.14), constipation (Δ 4.39%, 95% CI 1.79-6.99), diarrhea (Δ 6.69%, 95% CI 3.25-10.13), headache (Δ 7.4%, 95% CI 3.51-11.09), chest pain (Δ 9.04%, 95% CI 5.20-12.88), and limb pain (Δ 4.07%, 95% CI 1.76-6.37) and intensity of nausea (Δ 0.23, 95% CI 0.127-0.333), diarrhea (Δ 0.30, 95% CI 0.211-0.389), abdominal pain (Δ 0.18, 95% CI 0.069-0.291), headache (Δ 0.17, 95% CI 0.091-0.249), and limb pain (Δ 0.30, 95% CI 0.084-0.516) were higher in children with FGIDs (P < 0.001). Children with FGIDs had greater interference with daily activities (P < 0.001).CONCLUSIONS: Children with a Rome III diagnosis had significantly more gastrointestinal and nongastrointestinal complaints, and greater intensity of symptoms and disability than children without an FGID diagnosis. The study suggests that the Rome III pediatric criteria have adequate construct validity.

AB - OBJECTIVES: Functional gastrointestinal disorders (FGIDs) are common. The diagnosis of FGIDs is based on the Rome criteria, a symptom-based diagnostic classification established by expert consensus. There is little evidence of validity for the pediatric Rome III criteria. The construct validity of the criteria, an overarching term that incorporates other forms of validity, has never been assessed. We assessed the construct validity of the Rome III criteria.METHODS: Children from 2 schools in Colombia completed the Questionnaire on Pediatric Gastrointestinal Symptoms at baseline and weekly questionnaires of somatic symptoms and disability for 8 weeks (presence and intensity of gastrointestinal symptoms, nongastrointestinal symptoms, impact on daily activities). A total of 255 children completed at least 6 weekly surveys (2041 surveys).RESULTS: At baseline, 27.8% children were diagnosed as having an FGID. Prevalence of nausea (Δ 7.8%, 95% confidence interval [CI] 4.46-11.14), constipation (Δ 4.39%, 95% CI 1.79-6.99), diarrhea (Δ 6.69%, 95% CI 3.25-10.13), headache (Δ 7.4%, 95% CI 3.51-11.09), chest pain (Δ 9.04%, 95% CI 5.20-12.88), and limb pain (Δ 4.07%, 95% CI 1.76-6.37) and intensity of nausea (Δ 0.23, 95% CI 0.127-0.333), diarrhea (Δ 0.30, 95% CI 0.211-0.389), abdominal pain (Δ 0.18, 95% CI 0.069-0.291), headache (Δ 0.17, 95% CI 0.091-0.249), and limb pain (Δ 0.30, 95% CI 0.084-0.516) were higher in children with FGIDs (P < 0.001). Children with FGIDs had greater interference with daily activities (P < 0.001).CONCLUSIONS: Children with a Rome III diagnosis had significantly more gastrointestinal and nongastrointestinal complaints, and greater intensity of symptoms and disability than children without an FGID diagnosis. The study suggests that the Rome III pediatric criteria have adequate construct validity.

KW - Activities of Daily Living

KW - Child

KW - Colombia/epidemiology

KW - Constipation/diagnosis

KW - Diagnosis, Differential

KW - Diarrhea/diagnosis

KW - Female

KW - Gastrointestinal Diseases/complications

KW - Health Surveys

KW - Humans

KW - Male

KW - Nausea/diagnosis

KW - Pain/diagnosis

KW - Prevalence

KW - Severity of Illness Index

KW - Surveys and Questionnaires

KW - Symptom Assessment

U2 - 10.1097/MPG.0000000000000482

DO - 10.1097/MPG.0000000000000482

M3 - Article

VL - 59

SP - 577

EP - 581

JO - Journal of Pediatric Gastroenterology and Nutrition

JF - Journal of Pediatric Gastroenterology and Nutrition

SN - 0277-2116

IS - 5

ER -