Correction for desynchronization of EEG and fMRI clocks through data interpolation optimizes artifact reduction

Sónia I. Gonçalves*, Petra J.W. Pouwels, Joost P.A. Kuijer, Rob M. Heethaar, Jan C. De Munck

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Co-registration of EEG (Electroencephalogram)-and fMRI (functional magnetic resonance imaging) remains a challenge due to the large artifacts induced on the EEG by the MR (magnetic resonance) sequence gradient and RF pulses. We present an algorithm, based on the average-subtraction method, which is able to correct EEG data for gradient and RF pulse artifacts. We optimized artifact reduction by correcting the misalignment of EEG and fMRI data samples, resulting from the asynchronous sampling of EEG and fMRI data, through interpolation of EEG data. A clustering algorithm is proposed to account for the variability of the pulse artifact. Results show that the algorithm was able to keep the spontaneous brain activity while removing gradient and pulse artifacts with only a subtraction of selectively averaged data. Pulse artifact clustering showed that most of the variability was due to the time jitter of the pulse artifact markers. We show that artifact reduction by average-subtraction is optimized by interpolating the EEG data to correct for asynchronously sampled EEG and fMRI data.

Original languageEnglish
Title of host publication29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Pages1590-1594
Number of pages5
DOIs
Publication statusPublished - 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: 23 Aug 200726 Aug 2007

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)0589-1019

Conference

Conference29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period23/08/200726/08/2007

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