Abstract
SETTING: Cape Town, South Africa, 2014. OBJECTIVES: To assess the societal costs and cost-effectiveness of home-based vs. in-hospital treatment of paediatric tuberculous meningitis. DESIGN: This was an economic evaluation from a societal perspective using probabilistic analysis. Health care, informal care, lost productivity costs and costs in other sectors, health-related quality of life (HRQoL) and family impact were assessed during interviews with care givers, children, medical staff and management. RESULTS: Societal costs for home-based treatment were USD3857, and USD28 043 for in-hospital treatment. Home-based vs. in-hospital treatment HRQoL scores were 90.9% vs. 84.5%, while family impact scores were 94.8% vs. 73.1%. The point estimate of the incremental cost-effectiveness ratio indicated that improving HRQoL and family impact by 1% was associated with a saving of respectively USD3726 and USD1140 for home-based vs. in-hospital treatment. The probability that home-based treatment was less expensive and more effective than in-hospital treatment was 96.3% for HRQoL and 100% for family impact. CONCLUSIONS: Societal costs of home-based treatment were lower than for in-hospital treatment. Children treated at home had a better HRQoL and family impact scores. Home-based treatment was a cost-effective alternative to in-hospital treatment of drug-susceptible tuberculous meningitis.
| Original language | English |
|---|---|
| Pages (from-to) | 1188-1195 |
| Number of pages | 8 |
| Journal | International Journal of Tuberculosis and Lung Disease |
| Volume | 22 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 1 Oct 2018 |
Cite this
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Cost-effectiveness of home-based vs. in-hospital treatment of paediatric tuberculous meningitis. / Van Elsland, S. L.; Van Dongen, S. I.; Bosmans, J. E.; Schaaf, H. S.; Van Toorn, R.; Van Furth, A. M.
In: International Journal of Tuberculosis and Lung Disease, Vol. 22, No. 10, 01.10.2018, p. 1188-1195.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Cost-effectiveness of home-based vs. in-hospital treatment of paediatric tuberculous meningitis
AU - Van Elsland, S. L.
AU - Van Dongen, S. I.
AU - Bosmans, J. E.
AU - Schaaf, H. S.
AU - Van Toorn, R.
AU - Van Furth, A. M.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - SETTING: Cape Town, South Africa, 2014. OBJECTIVES: To assess the societal costs and cost-effectiveness of home-based vs. in-hospital treatment of paediatric tuberculous meningitis. DESIGN: This was an economic evaluation from a societal perspective using probabilistic analysis. Health care, informal care, lost productivity costs and costs in other sectors, health-related quality of life (HRQoL) and family impact were assessed during interviews with care givers, children, medical staff and management. RESULTS: Societal costs for home-based treatment were USD3857, and USD28 043 for in-hospital treatment. Home-based vs. in-hospital treatment HRQoL scores were 90.9% vs. 84.5%, while family impact scores were 94.8% vs. 73.1%. The point estimate of the incremental cost-effectiveness ratio indicated that improving HRQoL and family impact by 1% was associated with a saving of respectively USD3726 and USD1140 for home-based vs. in-hospital treatment. The probability that home-based treatment was less expensive and more effective than in-hospital treatment was 96.3% for HRQoL and 100% for family impact. CONCLUSIONS: Societal costs of home-based treatment were lower than for in-hospital treatment. Children treated at home had a better HRQoL and family impact scores. Home-based treatment was a cost-effective alternative to in-hospital treatment of drug-susceptible tuberculous meningitis.
AB - SETTING: Cape Town, South Africa, 2014. OBJECTIVES: To assess the societal costs and cost-effectiveness of home-based vs. in-hospital treatment of paediatric tuberculous meningitis. DESIGN: This was an economic evaluation from a societal perspective using probabilistic analysis. Health care, informal care, lost productivity costs and costs in other sectors, health-related quality of life (HRQoL) and family impact were assessed during interviews with care givers, children, medical staff and management. RESULTS: Societal costs for home-based treatment were USD3857, and USD28 043 for in-hospital treatment. Home-based vs. in-hospital treatment HRQoL scores were 90.9% vs. 84.5%, while family impact scores were 94.8% vs. 73.1%. The point estimate of the incremental cost-effectiveness ratio indicated that improving HRQoL and family impact by 1% was associated with a saving of respectively USD3726 and USD1140 for home-based vs. in-hospital treatment. The probability that home-based treatment was less expensive and more effective than in-hospital treatment was 96.3% for HRQoL and 100% for family impact. CONCLUSIONS: Societal costs of home-based treatment were lower than for in-hospital treatment. Children treated at home had a better HRQoL and family impact scores. Home-based treatment was a cost-effective alternative to in-hospital treatment of drug-susceptible tuberculous meningitis.
KW - Cost-effectiveness
KW - Home-based treatment
KW - Paediatric
KW - TBM
UR - http://www.scopus.com/inward/record.url?scp=85053829607&partnerID=8YFLogxK
U2 - 10.5588/ijtld.18.0236
DO - 10.5588/ijtld.18.0236
M3 - Article
VL - 22
SP - 1188
EP - 1195
JO - International Journal of Tuberculosis and Lung Disease
JF - International Journal of Tuberculosis and Lung Disease
SN - 1027-3719
IS - 10
ER -