De invloed van wittestofafwijkingen op ouderdomsdepressies

F. B. Van Der Wurff; A. T.F. Beekman; D. J. Veltman; W. J.G. Hoogendijk; Ph Scheltens; H. C. Weinstein

De invloed van wittestofafwijkingen op ouderdomsdepressies

Translated title of the contribution: The influence of white matter lesions on geriatric depressions

F. B. Van Der Wurff, A. T.F. Beekman, D. J. Veltman, W. J.G. Hoogendijk, Ph Scheltens, H. C. Weinstein

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

BACKGROUND: White matter lesions are recognisable as hyperintense lesions on Magnetic Resonance Imaging. These white matter lesions occur regularly in depressed elderly, especially in those with a late-onset depression. However, the relevance of white matter lesions for late-life depression remains obscure. They also occur in the non-depressive elderly. AIMS: This review article describes the relevance of white matter lesions of the brain for the aetiology, the symptomatology and the course of depression in the elderly. METHODS: Articles considering the relation between white matter lesions and late-life depressions were selected by means of a search in Medline. RESULTS: White matter lesions can influence the symptoms of late-life depressions. Especially subcortical white matter lesions seriously affect the outcome of late-life depressions. CONCLUSIONS: The presence of white matter lesions has major consequences for the treatment of late-life depressions.

Translated title of the contribution	The influence of white matter lesions on geriatric depressions
Original language	Dutch
Pages (from-to)	595-604
Number of pages	10
Journal	Tijdschrift voor Psychiatrie
Volume	42
Issue number	8
Publication status	Published - 1 Dec 2000

Cite this

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title = "De invloed van wittestofafwijkingen op ouderdomsdepressies",

abstract = "BACKGROUND: White matter lesions are recognisable as hyperintense lesions on Magnetic Resonance Imaging. These white matter lesions occur regularly in depressed elderly, especially in those with a late-onset depression. However, the relevance of white matter lesions for late-life depression remains obscure. They also occur in the non-depressive elderly. AIMS: This review article describes the relevance of white matter lesions of the brain for the aetiology, the symptomatology and the course of depression in the elderly. METHODS: Articles considering the relation between white matter lesions and late-life depressions were selected by means of a search in Medline. RESULTS: White matter lesions can influence the symptoms of late-life depressions. Especially subcortical white matter lesions seriously affect the outcome of late-life depressions. CONCLUSIONS: The presence of white matter lesions has major consequences for the treatment of late-life depressions.",

keywords = "Early-onset depression, Geriatric depression, Late-onset depression, MRI, Review, White matter lesions",

author = "{Van Der Wurff}, {F. B.} and Beekman, {A. T.F.} and Veltman, {D. J.} and Hoogendijk, {W. J.G.} and Ph Scheltens and Weinstein, {H. C.}",

year = "2000",

month = dec,

day = "1",

language = "Dutch",

volume = "42",

pages = "595--604",

journal = "Tijdschrift voor Psychiatrie",

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TY - JOUR

T1 - De invloed van wittestofafwijkingen op ouderdomsdepressies

AU - Van Der Wurff, F. B.

AU - Beekman, A. T.F.

AU - Veltman, D. J.

AU - Hoogendijk, W. J.G.

AU - Scheltens, Ph

AU - Weinstein, H. C.

PY - 2000/12/1

Y1 - 2000/12/1

N2 - BACKGROUND: White matter lesions are recognisable as hyperintense lesions on Magnetic Resonance Imaging. These white matter lesions occur regularly in depressed elderly, especially in those with a late-onset depression. However, the relevance of white matter lesions for late-life depression remains obscure. They also occur in the non-depressive elderly. AIMS: This review article describes the relevance of white matter lesions of the brain for the aetiology, the symptomatology and the course of depression in the elderly. METHODS: Articles considering the relation between white matter lesions and late-life depressions were selected by means of a search in Medline. RESULTS: White matter lesions can influence the symptoms of late-life depressions. Especially subcortical white matter lesions seriously affect the outcome of late-life depressions. CONCLUSIONS: The presence of white matter lesions has major consequences for the treatment of late-life depressions.

AB - BACKGROUND: White matter lesions are recognisable as hyperintense lesions on Magnetic Resonance Imaging. These white matter lesions occur regularly in depressed elderly, especially in those with a late-onset depression. However, the relevance of white matter lesions for late-life depression remains obscure. They also occur in the non-depressive elderly. AIMS: This review article describes the relevance of white matter lesions of the brain for the aetiology, the symptomatology and the course of depression in the elderly. METHODS: Articles considering the relation between white matter lesions and late-life depressions were selected by means of a search in Medline. RESULTS: White matter lesions can influence the symptoms of late-life depressions. Especially subcortical white matter lesions seriously affect the outcome of late-life depressions. CONCLUSIONS: The presence of white matter lesions has major consequences for the treatment of late-life depressions.

KW - Early-onset depression

KW - Geriatric depression

KW - Late-onset depression

KW - MRI

KW - Review

KW - White matter lesions

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M3 - Article

AN - SCOPUS:0034535158

VL - 42

SP - 595

EP - 604

JO - Tijdschrift voor Psychiatrie

JF - Tijdschrift voor Psychiatrie

SN - 0303-7339

IS - 8

ER -

De invloed van wittestofafwijkingen op ouderdomsdepressies

Abstract

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