TY - JOUR
T1 - Defining the characteristics and expectations of fluid bolus therapy: A worldwide perspective
T2 - Journal of Critical Care
AU - Glassford, N. J.
AU - Martensson, J.
AU - Eastwood, G. M.
AU - Lewis-Jones, S.
AU - Tanaka, A.
AU - Wilkman, E.
AU - Bailey, K.M.
AU - Bellomo, R.
AU - Arabi, Y.
AU - Bagshaw, S.M.
AU - Bannard-Smith, J.
AU - Buchanan, D. D.
AU - Dubin, A.
AU - Duranteau, J.
AU - Echeverri, J.
AU - Hoste, E.
AU - Joannidis, M.
AU - Kashani, K.
AU - Kellum, J.A.
AU - Kulkarni, A. P.
AU - Landoni, G.
AU - Candal, C. L.
AU - Matejovic, M.
AU - Yunos, N. M.
AU - Anaes, M.
AU - Nichol, A.
AU - Oudemans-van Straaten, Heleen
AU - Perner, A.
AU - Pettila, V.
AU - Phua, J.
AU - Hernandez, G.
AU - Puxty, A.
AU - Reinhart, K.
AU - Richards, William G.
AU - Schneider, A.
AU - Tsuji, I.
AU - Uchino, S.
AU - I, G. Lobal OBservational Evaluations
N1 - ISI Document Delivery No.: DX9KM Times Cited: 2 Cited Reference Count: 33 Glassford, Neil J. Martensson, Johan Eastwood, Glenn M. Jones, Sarah L. Tanaka, Aiko Wilkman, Erica Bailey, Michael Bellomo, Rinaldo Arabi, Yaseen Bagshaw, Sean M. Bannard-Smith, Jonathan Bin, Du Dubin, Arnaldo Duranteau, Jacques Echeverri, Jorge Hoste, Eric Joannidis, Michael Kashani, Kianoush Kellum, John Kulkarni, Atul P. Landoni, Giovanni Candal, Christina Lluch Matejovic, Martin Yunos, Norazim Modh Anaes, M. Nichol, Alistair Oudemans van Straaten, Heleen Perner, Anders Pettila, Ville Phua, Jason Hernandez, Glenn Puxty, Alex Reinhart, Konrad Richards, Guy Schneider, Antoine Tsuji, Isabella Uchino, Shigehiko Martensson, Johan/0000-0001-8739-7896; Nichol, Alistair/0000-0002-4689-1238; LANDONI, Giovanni/0000-0002-8594-5980; bailey, michael/0000-0002-5551-1401 Austin Hospital Anaesthesia and Intensive Care Trust Fund; Avant Doctors-In-Training Research Scholarship The Avant Doctors-In-Training Research Scholarship supports Dr Glassford. This study was supported by an unrestricted educational grant from the Austin Hospital Anaesthesia and Intensive Care Trust Fund. 2 8 W B SAUNDERS CO-ELSEVIER INC PHILADELPHIA J CRIT CARE
PY - 2016
Y1 - 2016
N2 - Purpose: The purpose of the study is to understand what clinicians believe defines fluid bolus therapy (FBT) and the expected response to such intervention. Methods: We asked intensive care specialists in 30 countries to participate in an electronic questionnaire of their practice, definition, and expectations of FBT. Results: We obtained 3138 responses. Despite much variation, more than 80% of respondents felt that more than 250 mL of either colloid or crystalloid fluid given over less than 30 minutes defined FBT, with crystalloids most acceptable. The most acceptable crystalloid and colloid for use as FBT were 0.9% saline and 4% albumin solution, respectively. Most respondents believed that one or more of the following physiological changes indicates a response to FBT: a mean arterial pressure increase greater than 10 mm Hg, a heart rate decrease greater than 10 beats per minute, an increase in urinary output by more than 10 mL/h, an increase in central venous oxygen saturation greater than 4%, or a lactate decrease greater than 1 mmol/L. Conclusions: Despite wide variability between individuals and countries, clear majority views emerged to describe practice, define FBT, and identify a response to it. Further investigation is now required to describe actual FBT practice and to identify the magnitude and duration of the physiological response to FBT and its relationship to patient-centered outcomes. (C) 2016 Elsevier Inc. All rights reserved.
AB - Purpose: The purpose of the study is to understand what clinicians believe defines fluid bolus therapy (FBT) and the expected response to such intervention. Methods: We asked intensive care specialists in 30 countries to participate in an electronic questionnaire of their practice, definition, and expectations of FBT. Results: We obtained 3138 responses. Despite much variation, more than 80% of respondents felt that more than 250 mL of either colloid or crystalloid fluid given over less than 30 minutes defined FBT, with crystalloids most acceptable. The most acceptable crystalloid and colloid for use as FBT were 0.9% saline and 4% albumin solution, respectively. Most respondents believed that one or more of the following physiological changes indicates a response to FBT: a mean arterial pressure increase greater than 10 mm Hg, a heart rate decrease greater than 10 beats per minute, an increase in urinary output by more than 10 mL/h, an increase in central venous oxygen saturation greater than 4%, or a lactate decrease greater than 1 mmol/L. Conclusions: Despite wide variability between individuals and countries, clear majority views emerged to describe practice, define FBT, and identify a response to it. Further investigation is now required to describe actual FBT practice and to identify the magnitude and duration of the physiological response to FBT and its relationship to patient-centered outcomes. (C) 2016 Elsevier Inc. All rights reserved.
U2 - 10.1016/j.jcrc.2016.05.017
DO - 10.1016/j.jcrc.2016.05.017
M3 - Article
C2 - 27481747
VL - 35
SP - 126
EP - 132
JO - Journal of Critical Care
JF - Journal of Critical Care
SN - 0883-9441
ER -