Determinants of compliance with methylphenidate therapy in children

Jacqueline G. Hugtenburg, Ivo Witte, Eibert R. Heerdink

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Aim: To get more insight into factors that influence compliance with the use of methylphenidate. Methods: 22 pharmacies detected children who used methylphenidate. Their parents were sent a questionnaire on the use of methylphenidate. In a case-control study, the influence of patient- and drug-related factors on compliance, as reported by parents, was determined. Results: Parents returned 117 (75%) of 157 questionnaires sent out. Of these, 47.8% of the children missed a dose two times a month or more. Forgetting to take the medication (87.9%) was the most important reason. The case-control study showed that children of 16-18 y were more likely to miss doses. Other patient- and drug-related factors did not influence the missing of doses. Conclusion: A number of known determinants for compliance do not influence the missing of doses of methylphenidate. With about 80% of the parents reporting that their child missed doses of methylphenidate less than 5 times per month, compliance was quite good for the majority of the children.

Original languageEnglish
Pages (from-to)1674-1676
Number of pages3
JournalActa Paediatrica, International Journal of Paediatrics
Volume95
Issue number12
DOIs
Publication statusPublished - 1 Dec 2006

Cite this

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abstract = "Aim: To get more insight into factors that influence compliance with the use of methylphenidate. Methods: 22 pharmacies detected children who used methylphenidate. Their parents were sent a questionnaire on the use of methylphenidate. In a case-control study, the influence of patient- and drug-related factors on compliance, as reported by parents, was determined. Results: Parents returned 117 (75{\%}) of 157 questionnaires sent out. Of these, 47.8{\%} of the children missed a dose two times a month or more. Forgetting to take the medication (87.9{\%}) was the most important reason. The case-control study showed that children of 16-18 y were more likely to miss doses. Other patient- and drug-related factors did not influence the missing of doses. Conclusion: A number of known determinants for compliance do not influence the missing of doses of methylphenidate. With about 80{\%} of the parents reporting that their child missed doses of methylphenidate less than 5 times per month, compliance was quite good for the majority of the children.",
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Determinants of compliance with methylphenidate therapy in children. / Hugtenburg, Jacqueline G.; Witte, Ivo; Heerdink, Eibert R.

In: Acta Paediatrica, International Journal of Paediatrics, Vol. 95, No. 12, 01.12.2006, p. 1674-1676.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Hugtenburg, Jacqueline G.

AU - Witte, Ivo

AU - Heerdink, Eibert R.

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N2 - Aim: To get more insight into factors that influence compliance with the use of methylphenidate. Methods: 22 pharmacies detected children who used methylphenidate. Their parents were sent a questionnaire on the use of methylphenidate. In a case-control study, the influence of patient- and drug-related factors on compliance, as reported by parents, was determined. Results: Parents returned 117 (75%) of 157 questionnaires sent out. Of these, 47.8% of the children missed a dose two times a month or more. Forgetting to take the medication (87.9%) was the most important reason. The case-control study showed that children of 16-18 y were more likely to miss doses. Other patient- and drug-related factors did not influence the missing of doses. Conclusion: A number of known determinants for compliance do not influence the missing of doses of methylphenidate. With about 80% of the parents reporting that their child missed doses of methylphenidate less than 5 times per month, compliance was quite good for the majority of the children.

AB - Aim: To get more insight into factors that influence compliance with the use of methylphenidate. Methods: 22 pharmacies detected children who used methylphenidate. Their parents were sent a questionnaire on the use of methylphenidate. In a case-control study, the influence of patient- and drug-related factors on compliance, as reported by parents, was determined. Results: Parents returned 117 (75%) of 157 questionnaires sent out. Of these, 47.8% of the children missed a dose two times a month or more. Forgetting to take the medication (87.9%) was the most important reason. The case-control study showed that children of 16-18 y were more likely to miss doses. Other patient- and drug-related factors did not influence the missing of doses. Conclusion: A number of known determinants for compliance do not influence the missing of doses of methylphenidate. With about 80% of the parents reporting that their child missed doses of methylphenidate less than 5 times per month, compliance was quite good for the majority of the children.

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