Determinants of end-systolic elastance of the left ventricle and their relationship with volumetric indices

Peter L M Kerkhof*, Eric L M Pijnenburg

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

The aim of this study is to analyze how the End-Systolic Pressure-Volume Relationship (ESPVR) depends an ventricular volume in the diseased left ventricle. Ventricular end-systolic elastance (Emax) varies with the prevailing values of ejection pressure (ESP), end-systolic volume (ESV), and an unstressed volume term (Vo). Measurements on humans as reported in the literature are used to investigate the full range of this relationship. Our results indicate that considering Emax alone, as is usually done in clinical practice, is an insufficient approach to characterize ventricular function. Rather we propose to consider the easily attainable yet more powerful index ESV. Interestingly, ESV is also significantly correlated with the term (ESV-Vo), suggesting that ESV in itself already embodies information on this elementary index Vo.

Original languageEnglish
Title of host publicationEMBS
Pages1322-1323
Number of pages2
Volume3
Publication statusPublished - 1 Dec 1996
EventProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 4 (of 5) - Amsterdam, Neth
Duration: 31 Oct 19963 Nov 1996

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)0589-1019

Conference

ConferenceProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 4 (of 5)
CityAmsterdam, Neth
Period31/10/199603/11/1996

Cite this

Kerkhof, P. L. M., & Pijnenburg, E. L. M. (1996). Determinants of end-systolic elastance of the left ventricle and their relationship with volumetric indices. In EMBS (Vol. 3, pp. 1322-1323). (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings).