Development of a 70 MHz unit for hyperthermia treatment of deep seated breast tumors

J. Crezee, G. van Tienhoven, M. W. Kolff, J. Sijbrands, G. van Stam, S. Oldenborg, E. D. Geijsen, M. C. C. M. Hulshof, H. P. Kok

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Hyperthermia of tumors in intact breast extending beyond the heating depth of our superficial 434 MHz CFMA antennas requires an alternative approach. A dedicated system was designed for this purpose, consisting of a treatment bed fitted with a 50×40×16cm temperature controlled open water bolus. The patient lies in prone position with the breast immersed in the water positioned in front of a 34×20cm 70 MHz waveguide placed in the bottom of the bolus. Hyperthermia was applied once a week for the whole breast with the 70 MHz applicator for 6 patients treated with thermoradiotherapy for deep lesions of recurrent breast cancer or melanoma. Two 14-sensor thermocouple thermometry probes were placed in catheters to monitor the invasive temperature. Results: The combination of 300-900W antenna power and a water temperature of 42°C was well tolerated for the entire session of one hour and resulted in good tumor temperatures with T10 = 42.2°C, T50 = 41.1°C, T90 = 39.8°C. No toxicity or complaints were associated with the heating. A water mattress and other measures were needed to assure a comfortable position throughout the treatment. Conclusion: the 70 MHz breast applicator system performed well and tumor temperatures were good.
Original languageEnglish
Title of host publicationEuropean Microwave Week 2016: "Microwaves Everywhere", EuMW 2016 - Conference Proceedings; 46th European Microwave Conference, EuMC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages906-909
ISBN (Electronic)9782874870439
DOIs
Publication statusPublished - 2016
Externally publishedYes
Event46th European Microwave Conference, EuMC 2016 - London, United Kingdom
Duration: 4 Oct 20166 Oct 2016

Publication series

NameEuropean Microwave Week 2016: "Microwaves Everywhere", EuMW 2016 - Conference Proceedings; 46th European Microwave Conference, EuMC 2016

Conference

Conference46th European Microwave Conference, EuMC 2016
CountryUnited Kingdom
CityLondon
Period04/10/201606/10/2016

Cite this

Crezee, J., van Tienhoven, G., Kolff, M. W., Sijbrands, J., van Stam, G., Oldenborg, S., ... Kok, H. P. (2016). Development of a 70 MHz unit for hyperthermia treatment of deep seated breast tumors. In European Microwave Week 2016: "Microwaves Everywhere", EuMW 2016 - Conference Proceedings; 46th European Microwave Conference, EuMC 2016 (pp. 906-909). (European Microwave Week 2016: "Microwaves Everywhere", EuMW 2016 - Conference Proceedings; 46th European Microwave Conference, EuMC 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EuMC.2016.7824491