Discovery of a γ-carboxyglutamic acid-containing protein in human spermatozoa

Berry A M Soute*, Werner Müller-Esterl, Marian A G de Boer-van den Berg, Magda Ulrich, Cees Vermeer

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Here we describe the identification of a γ-carboxyglutamic acid-containing protein in human spermatozoa. After thermal decarboxylation the protein is a good substrate for vitamin K-dependent carboxylase from various origins. A quick purification procedure for the decarboxylated protein is presented and in a preliminary characterization we have established its Mr, (28000-30000) and its amino acid composition.

Original languageEnglish
Pages (from-to)137-141
Number of pages5
JournalFEBS Letters
Volume190
Issue number1
DOIs
Publication statusPublished - 7 Oct 1985

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