Distribution of trabecular and cortical bone related to geometry. A quantitative computed tomography study of the femoral neck

J W Kuiper, C Van Kuijk, J L Grashuis

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

METHODS: The relation between geometry and the distribution of trabecular and cortical bone mass and density in the human femoral neck was evaluated with quantitative computed tomography (QCT). Quantitative computed tomography data were obtained from 2-mm thick computed tomography slices of 20 human femur necks in vitro. A standardized scan position in each femur was used with the smallest cross-section as reference point.

RESULTS: When trabecular bone mass (TrBM) and cortical bone mass were presented as percentage of total bone mass (ToBM), it was found that, starting at the cranial (head) side, ToBM consists of 78% TrBM. About 21% of ToBM can be found as TrBM at the caudal (trochanter) side. At the smallest cross-sectional volume TrBM is 33% of ToBM. For every 2-mm slice, an average decrease of 5% TrBM can be seen.

CONCLUSIONS: These data show that geometry and bone mass distribution are related. Whereas total bone mass remains relatively stable, the cortical and trabecular bone mass changes extensively. This implies that QCT measurements in the femoral neck depend highly on midneck positioning.

LanguageEnglish
Pages83-9
Number of pages7
JournalInvestigative Radiology
Volume32
Issue number2
Publication statusPublished - Feb 1997

Cite this

@article{603210bc30024f07b3439a2d1d4a1601,
title = "Distribution of trabecular and cortical bone related to geometry. A quantitative computed tomography study of the femoral neck",
abstract = "METHODS: The relation between geometry and the distribution of trabecular and cortical bone mass and density in the human femoral neck was evaluated with quantitative computed tomography (QCT). Quantitative computed tomography data were obtained from 2-mm thick computed tomography slices of 20 human femur necks in vitro. A standardized scan position in each femur was used with the smallest cross-section as reference point.RESULTS: When trabecular bone mass (TrBM) and cortical bone mass were presented as percentage of total bone mass (ToBM), it was found that, starting at the cranial (head) side, ToBM consists of 78{\%} TrBM. About 21{\%} of ToBM can be found as TrBM at the caudal (trochanter) side. At the smallest cross-sectional volume TrBM is 33{\%} of ToBM. For every 2-mm slice, an average decrease of 5{\%} TrBM can be seen.CONCLUSIONS: These data show that geometry and bone mass distribution are related. Whereas total bone mass remains relatively stable, the cortical and trabecular bone mass changes extensively. This implies that QCT measurements in the femoral neck depend highly on midneck positioning.",
keywords = "Absorptiometry, Photon, Aged, Aged, 80 and over, Bone Density, Female, Femur Neck, Humans, In Vitro Techniques, Male, Tomography, X-Ray Computed, Journal Article",
author = "Kuiper, {J W} and {Van Kuijk}, C and Grashuis, {J L}",
year = "1997",
month = "2",
language = "English",
volume = "32",
pages = "83--9",
journal = "Invest Radiol",
issn = "0020-9996",
publisher = "Lippincott Williams and Wilkins Ltd.",
number = "2",

}

Distribution of trabecular and cortical bone related to geometry. A quantitative computed tomography study of the femoral neck. / Kuiper, J W; Van Kuijk, C; Grashuis, J L.

In: Investigative Radiology, Vol. 32, No. 2, 02.1997, p. 83-9.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Distribution of trabecular and cortical bone related to geometry. A quantitative computed tomography study of the femoral neck

AU - Kuiper, J W

AU - Van Kuijk, C

AU - Grashuis, J L

PY - 1997/2

Y1 - 1997/2

N2 - METHODS: The relation between geometry and the distribution of trabecular and cortical bone mass and density in the human femoral neck was evaluated with quantitative computed tomography (QCT). Quantitative computed tomography data were obtained from 2-mm thick computed tomography slices of 20 human femur necks in vitro. A standardized scan position in each femur was used with the smallest cross-section as reference point.RESULTS: When trabecular bone mass (TrBM) and cortical bone mass were presented as percentage of total bone mass (ToBM), it was found that, starting at the cranial (head) side, ToBM consists of 78% TrBM. About 21% of ToBM can be found as TrBM at the caudal (trochanter) side. At the smallest cross-sectional volume TrBM is 33% of ToBM. For every 2-mm slice, an average decrease of 5% TrBM can be seen.CONCLUSIONS: These data show that geometry and bone mass distribution are related. Whereas total bone mass remains relatively stable, the cortical and trabecular bone mass changes extensively. This implies that QCT measurements in the femoral neck depend highly on midneck positioning.

AB - METHODS: The relation between geometry and the distribution of trabecular and cortical bone mass and density in the human femoral neck was evaluated with quantitative computed tomography (QCT). Quantitative computed tomography data were obtained from 2-mm thick computed tomography slices of 20 human femur necks in vitro. A standardized scan position in each femur was used with the smallest cross-section as reference point.RESULTS: When trabecular bone mass (TrBM) and cortical bone mass were presented as percentage of total bone mass (ToBM), it was found that, starting at the cranial (head) side, ToBM consists of 78% TrBM. About 21% of ToBM can be found as TrBM at the caudal (trochanter) side. At the smallest cross-sectional volume TrBM is 33% of ToBM. For every 2-mm slice, an average decrease of 5% TrBM can be seen.CONCLUSIONS: These data show that geometry and bone mass distribution are related. Whereas total bone mass remains relatively stable, the cortical and trabecular bone mass changes extensively. This implies that QCT measurements in the femoral neck depend highly on midneck positioning.

KW - Absorptiometry, Photon

KW - Aged

KW - Aged, 80 and over

KW - Bone Density

KW - Female

KW - Femur Neck

KW - Humans

KW - In Vitro Techniques

KW - Male

KW - Tomography, X-Ray Computed

KW - Journal Article

M3 - Article

VL - 32

SP - 83

EP - 89

JO - Invest Radiol

T2 - Invest Radiol

JF - Invest Radiol

SN - 0020-9996

IS - 2

ER -