Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder

Xiaochen Luo; Nikolaos Stavrakakis; Brenda W. Penninx; Fokko J. Bosker; Willem A. Nolen; Dorret I. Boomsma; Eco J. de Geus; Jan Smit; Harold Snieder; Ilja M. Nolte; Catharina A. Hartman

doi:10.1002/ajmg.b.32396

Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder

Xiaochen Luo, Nikolaos Stavrakakis, Brenda W. Penninx, Fokko J. Bosker, Willem A. Nolen, Dorret I. Boomsma, Eco J. de Geus, Jan Smit, Harold Snieder, Ilja M. Nolte, Catharina A. Hartman

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	215-236
Journal	American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Volume	171
Issue number	2
DOIs	https://doi.org/10.1002/ajmg.b.32396
Publication status	Published - Mar 2016

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10.1002/ajmg.b.32396

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Luo, X., Stavrakakis, N., Penninx, B. W., Bosker, F. J., Nolen, W. A., Boomsma, D. I., de Geus, E. J., Smit, J., Snieder, H., Nolte, I. M., & Hartman, C. A. (2016). Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 171(2), 215-236. https://doi.org/10.1002/ajmg.b.32396

Luo, Xiaochen ; Stavrakakis, Nikolaos ; Penninx, Brenda W. ; Bosker, Fokko J. ; Nolen, Willem A. ; Boomsma, Dorret I. ; de Geus, Eco J. ; Smit, Jan ; Snieder, Harold ; Nolte, Ilja M. ; Hartman, Catharina A. / Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder. In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2016 ; Vol. 171, No. 2. pp. 215-236.

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title = "Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder",

keywords = "major depressive disorder, candidate genes, genome-wide association study, chronic depression, severe depression, replication",

author = "Xiaochen Luo and Nikolaos Stavrakakis and Penninx, {Brenda W.} and Bosker, {Fokko J.} and Nolen, {Willem A.} and Boomsma, {Dorret I.} and {de Geus}, {Eco J.} and Jan Smit and Harold Snieder and Nolte, {Ilja M.} and Hartman, {Catharina A.}",

year = "2016",

month = mar,

doi = "10.1002/ajmg.b.32396",

language = "English",

volume = "171",

pages = "215--236",

journal = "American Journal of Medical Genetics Part B: Neuropsychiatric Genetics",

issn = "1552-4841",

publisher = "Wiley-Liss Inc.",

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Luo, X, Stavrakakis, N, Penninx, BW, Bosker, FJ, Nolen, WA, Boomsma, DI, de Geus, EJ, Smit, J, Snieder, H, Nolte, IM & Hartman, CA 2016, 'Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, vol. 171, no. 2, pp. 215-236. https://doi.org/10.1002/ajmg.b.32396

Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder. / Luo, Xiaochen; Stavrakakis, Nikolaos; Penninx, Brenda W.; Bosker, Fokko J.; Nolen, Willem A.; Boomsma, Dorret I.; de Geus, Eco J.; Smit, Jan; Snieder, Harold; Nolte, Ilja M.; Hartman, Catharina A.

In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Vol. 171, No. 2, 03.2016, p. 215-236.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder

AU - Luo, Xiaochen

AU - Stavrakakis, Nikolaos

AU - Penninx, Brenda W.

AU - Bosker, Fokko J.

AU - Nolen, Willem A.

AU - Boomsma, Dorret I.

AU - de Geus, Eco J.

AU - Smit, Jan

AU - Snieder, Harold

AU - Nolte, Ilja M.

AU - Hartman, Catharina A.

PY - 2016/3

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KW - major depressive disorder

KW - candidate genes

KW - genome-wide association study

KW - chronic depression

KW - severe depression

KW - replication

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DO - 10.1002/ajmg.b.32396

M3 - Article

C2 - 26566975

VL - 171

SP - 215

EP - 236

JO - American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

JF - American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

SN - 1552-4841

IS - 2

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Luo X, Stavrakakis N, Penninx BW, Bosker FJ, Nolen WA, Boomsma DI et al. Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2016 Mar;171(2):215-236. https://doi.org/10.1002/ajmg.b.32396