E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET

Francesco Ceci, Daniela E. Oprea-Lager*, Louise Emmett, Judit A. Adam, Jamshed Bomanji, Johannes Czernin, Matthias Eiber, Uwe Haberkorn, Michael S. Hofman, Thomas A. Hope, Rakesh Kumar, Steven P. Rowe, Sarah M. Schwarzenboeck, Stefano Fanti, Ken Herrmann

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Rationale: The development of consensus guidelines for interpretation of Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) is needed to provide more consistent reports in clinical practice. The standardization of PSMA-PET interpretation may also contribute to increasing the data reproducibility within clinical trials. Finally, guidelines in PSMA-PET interpretation are needed to communicate the exact location of findings to referring physicians, to support clinician therapeutic management decisions. Methods: A panel of worldwide experts in PSMA-PET was established. Panelists were selected based on their expertise and publication record in the diagnosis or treatment of PCa, in their involvement in clinical guidelines and according to their expertise in the clinical application of radiolabeled PSMA inhibitors. Panelists were actively involved in all stages of a modified, nonanonymous, Delphi consensus process. Results: According to the findings obtained by modified Delphi consensus process, panelist recommendations were implemented in a structured report for PSMA-PET. Conclusions: The E-PSMA standardized reporting guidelines, a document supported by the European Association of Nuclear Medicine (EANM), provide consensus statements among a panel of experts in PSMA-PET imaging, to develop a structured report for PSMA-PET in prostate cancer and to harmonize diagnostic interpretation criteria.
Original languageEnglish
Pages (from-to)1626-1638
Number of pages13
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Issue number5
Early online date2021
Publication statusPublished - May 2021

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