Een patiënt met visuele problemen: Eerste uiting van neurodegeneratieve aandoening

Translated title of the contribution: A patient with vision problems: First manifestation of a neurodegenerative condition

Marlijn De Beer*, Annebet Leeuwis, Yolande Pijnenburg

*Corresponding author for this work

Research output: Contribution to journalArticleProfessional

Abstract

Background: Vision problems are common and the causes are diverse. This case illustrates the fact that vision problems may also be the first manifestation of a neurodegenerative disorder. Case description: A 46yearold male developed progressive, incapacitating vision problems. Multiple pairs of glasses with lenses of different strengths did not improve symptoms. No ophthalmological explanation of the problems could be found. Oculomotor apraxia and visual extinction were seen on neurological examination. Visuoperceptual impairment was the main finding on neuropsychological examination. Impairment was also identified in visuoconstruction, memory and praxis. Conclusion: Cognitive problems in several areas, interference with activities of daily living, and young age of onset complete the clinical picture of presenile dementia. Posterior cortical atrophy is a spectrum of neurodegenerative disorders, characterized by progressive, incapacitating visuospatial and visuoperceptual impairment. The most prevalent underlying pathology is Alzheimer's disease. At present there is no curative therapy for posterior cortical atrophy.

Original languageDutch
Article numberA8878
JournalNederlands Tijdschrift voor Geneeskunde
Volume159
Issue number41
Publication statusPublished - 2015

Cite this