Effect of a titanium cage as a stand-alone device on biomechanical stability in the lumbosacral spine of canine cadavers

M. Teunissen, A. J. van der Veen, T. H. Smit, M. A. Tryfonidou, B. P. Meij

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    Degenerative lumbosacral stenosis is a common disease in dogs characterised by intervertebral disc herniation, loss of disc height and stenosis. Decompressive dorsal laminectomy and partial discectomy can cause spinal instability and worsen foraminal stenosis. Pedicle screw and rod fixation (PSRF) with an intervertebral body cage allows for distraction and restoration of disc height and restores foraminal apertures. The aim of this study was to evaluate the ex vivo biomechanical properties of a titanium intervertebral cage alone and in combination with PSRF in the lumbosacral spine of dogs. The range of motion, neutral zone, neutral zone stiffness and elastic zone stiffness of the lumbosacral joint (L7-S1) of nine canine cadavers were determined in flexion/extension, lateral bending and axial rotation for four conditions: (1) native (unmodified) spine; (2) dorsal laminectomy and discectomy; (3) stand-alone cage; and (4) cage in combination with PSRF. The intervertebral disc height decreased after dorsal laminectomy, but increased after insertion of the cage. Insertion of the stand-alone cage decreased the range of motion and neutral zone compared to the laminectomy-discectomy and increased neutral zone stiffness in all directions. The range of motion further decreased after PSRF. From a biomechanical point of view, the use of a stand-alone intervertebral cage is a potential alternative to dorsal fixation of the lumbosacral junction, since it increases spinal stability and restores disc height.

    Original languageEnglish
    Pages (from-to)17-23
    Number of pages7
    JournalVeterinary Journal
    Volume220
    DOIs
    Publication statusPublished - 1 Feb 2017

    Cite this

    @article{5196578132e84e6781cd71682745c0f2,
    title = "Effect of a titanium cage as a stand-alone device on biomechanical stability in the lumbosacral spine of canine cadavers",
    abstract = "Degenerative lumbosacral stenosis is a common disease in dogs characterised by intervertebral disc herniation, loss of disc height and stenosis. Decompressive dorsal laminectomy and partial discectomy can cause spinal instability and worsen foraminal stenosis. Pedicle screw and rod fixation (PSRF) with an intervertebral body cage allows for distraction and restoration of disc height and restores foraminal apertures. The aim of this study was to evaluate the ex vivo biomechanical properties of a titanium intervertebral cage alone and in combination with PSRF in the lumbosacral spine of dogs. The range of motion, neutral zone, neutral zone stiffness and elastic zone stiffness of the lumbosacral joint (L7-S1) of nine canine cadavers were determined in flexion/extension, lateral bending and axial rotation for four conditions: (1) native (unmodified) spine; (2) dorsal laminectomy and discectomy; (3) stand-alone cage; and (4) cage in combination with PSRF. The intervertebral disc height decreased after dorsal laminectomy, but increased after insertion of the cage. Insertion of the stand-alone cage decreased the range of motion and neutral zone compared to the laminectomy-discectomy and increased neutral zone stiffness in all directions. The range of motion further decreased after PSRF. From a biomechanical point of view, the use of a stand-alone intervertebral cage is a potential alternative to dorsal fixation of the lumbosacral junction, since it increases spinal stability and restores disc height.",
    keywords = "Biomechanical evaluation, Canine, Degenerative lumbosacral stenosis, Pedicle screw and rod fixation, Titanium intervertebral cage",
    author = "M. Teunissen and {van der Veen}, {A. J.} and Smit, {T. H.} and Tryfonidou, {M. A.} and Meij, {B. P.}",
    year = "2017",
    month = "2",
    day = "1",
    doi = "10.1016/j.tvjl.2016.12.007",
    language = "English",
    volume = "220",
    pages = "17--23",
    journal = "Veterinary Journal",
    issn = "1090-0233",
    publisher = "Bailliere Tindall Ltd",

    }

    Effect of a titanium cage as a stand-alone device on biomechanical stability in the lumbosacral spine of canine cadavers. / Teunissen, M.; van der Veen, A. J.; Smit, T. H.; Tryfonidou, M. A.; Meij, B. P.

    In: Veterinary Journal, Vol. 220, 01.02.2017, p. 17-23.

    Research output: Contribution to journalArticleAcademicpeer-review

    TY - JOUR

    T1 - Effect of a titanium cage as a stand-alone device on biomechanical stability in the lumbosacral spine of canine cadavers

    AU - Teunissen, M.

    AU - van der Veen, A. J.

    AU - Smit, T. H.

    AU - Tryfonidou, M. A.

    AU - Meij, B. P.

    PY - 2017/2/1

    Y1 - 2017/2/1

    N2 - Degenerative lumbosacral stenosis is a common disease in dogs characterised by intervertebral disc herniation, loss of disc height and stenosis. Decompressive dorsal laminectomy and partial discectomy can cause spinal instability and worsen foraminal stenosis. Pedicle screw and rod fixation (PSRF) with an intervertebral body cage allows for distraction and restoration of disc height and restores foraminal apertures. The aim of this study was to evaluate the ex vivo biomechanical properties of a titanium intervertebral cage alone and in combination with PSRF in the lumbosacral spine of dogs. The range of motion, neutral zone, neutral zone stiffness and elastic zone stiffness of the lumbosacral joint (L7-S1) of nine canine cadavers were determined in flexion/extension, lateral bending and axial rotation for four conditions: (1) native (unmodified) spine; (2) dorsal laminectomy and discectomy; (3) stand-alone cage; and (4) cage in combination with PSRF. The intervertebral disc height decreased after dorsal laminectomy, but increased after insertion of the cage. Insertion of the stand-alone cage decreased the range of motion and neutral zone compared to the laminectomy-discectomy and increased neutral zone stiffness in all directions. The range of motion further decreased after PSRF. From a biomechanical point of view, the use of a stand-alone intervertebral cage is a potential alternative to dorsal fixation of the lumbosacral junction, since it increases spinal stability and restores disc height.

    AB - Degenerative lumbosacral stenosis is a common disease in dogs characterised by intervertebral disc herniation, loss of disc height and stenosis. Decompressive dorsal laminectomy and partial discectomy can cause spinal instability and worsen foraminal stenosis. Pedicle screw and rod fixation (PSRF) with an intervertebral body cage allows for distraction and restoration of disc height and restores foraminal apertures. The aim of this study was to evaluate the ex vivo biomechanical properties of a titanium intervertebral cage alone and in combination with PSRF in the lumbosacral spine of dogs. The range of motion, neutral zone, neutral zone stiffness and elastic zone stiffness of the lumbosacral joint (L7-S1) of nine canine cadavers were determined in flexion/extension, lateral bending and axial rotation for four conditions: (1) native (unmodified) spine; (2) dorsal laminectomy and discectomy; (3) stand-alone cage; and (4) cage in combination with PSRF. The intervertebral disc height decreased after dorsal laminectomy, but increased after insertion of the cage. Insertion of the stand-alone cage decreased the range of motion and neutral zone compared to the laminectomy-discectomy and increased neutral zone stiffness in all directions. The range of motion further decreased after PSRF. From a biomechanical point of view, the use of a stand-alone intervertebral cage is a potential alternative to dorsal fixation of the lumbosacral junction, since it increases spinal stability and restores disc height.

    KW - Biomechanical evaluation

    KW - Canine

    KW - Degenerative lumbosacral stenosis

    KW - Pedicle screw and rod fixation

    KW - Titanium intervertebral cage

    UR - http://www.scopus.com/inward/record.url?scp=85011966124&partnerID=8YFLogxK

    U2 - 10.1016/j.tvjl.2016.12.007

    DO - 10.1016/j.tvjl.2016.12.007

    M3 - Article

    VL - 220

    SP - 17

    EP - 23

    JO - Veterinary Journal

    JF - Veterinary Journal

    SN - 1090-0233

    ER -