Effect on diagnostic yield of repeated stool testing during outbreaks of Clostridium difficile- associated disease

S. B. Debast*, E. Van Kregten, K. M.G. Oskam, T. Van Den Berg, R. J. Van Den Berg, E. J. Kuijper

*Corresponding author for this work

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The effect on diagnostic yield of testing sequential stools was assessed during two hospital epidemics of Clostridium difficile. Using a rapid immunoassay, C. difficile- associated disease was diagnosed in 237 diarrhoeal patients, of whom 204 (86%) were diagnosed from the first faeces sample and 12 (5%) were diagnosed from follow-up samples obtained within 1week. The remaining 21 (9%) patients yielded a positive test from stools obtained >1 week after the initial negative sample. It was concluded that repeated testing of stools for C. difficile toxin is of value in controlling outbreaks of C. difficile infection.

Original languageEnglish
Pages (from-to)622-624
Number of pages3
JournalClinical Microbiology and Infection
Issue number6
Publication statusPublished - Jun 2008
Externally publishedYes

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