Effects of the pure antiandrogen RU 23.903 (anandron) on sexuality, aggression, and mood in male-to-female transsexuals

Johannes F.L.M. van Kemenade, Peggy T. Cohen-Kettenis, Leo Cohen, Louis J.G. Gooren

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Sexuality, aggression, and mood were investigated in 14 presurgical male-to-female transsexuals, undergoing antiandrogenic treatment with anandron, a pure antiandrogen. Subjects were given a test battery the morning prior to treatment onset and after 8 weeks of treatment. In addition they were requested to complete daily forms concerned with sexual behavior and mood. Morning erections and the frequency of thoughts and fantasies about sex decreased after anandron intake. Aggressive feelings were uncorrelated with testosterone level. Moods such as level of energy, feelings of relaxation, fatigue, and feelings of tension and anxiety appeared to fluctuate more as a consequence of anandron intake than did moods such as cheerful, sociable and friendly, gloomy and unhappy, irritated and changeable. The latter remained at a constant level.

Original languageEnglish
Pages (from-to)217-228
Number of pages12
JournalArchives of Sexual Behavior
Volume18
Issue number3
DOIs
Publication statusPublished - 1 Jun 1989

Cite this

@article{c74d67e9ee484ce6b8c43bd3a386677a,
title = "Effects of the pure antiandrogen RU 23.903 (anandron) on sexuality, aggression, and mood in male-to-female transsexuals",
abstract = "Sexuality, aggression, and mood were investigated in 14 presurgical male-to-female transsexuals, undergoing antiandrogenic treatment with anandron, a pure antiandrogen. Subjects were given a test battery the morning prior to treatment onset and after 8 weeks of treatment. In addition they were requested to complete daily forms concerned with sexual behavior and mood. Morning erections and the frequency of thoughts and fantasies about sex decreased after anandron intake. Aggressive feelings were uncorrelated with testosterone level. Moods such as level of energy, feelings of relaxation, fatigue, and feelings of tension and anxiety appeared to fluctuate more as a consequence of anandron intake than did moods such as cheerful, sociable and friendly, gloomy and unhappy, irritated and changeable. The latter remained at a constant level.",
keywords = "aggression, anandron, fantasy, mood, sexuality, transsexuals",
author = "{van Kemenade}, {Johannes F.L.M.} and Cohen-Kettenis, {Peggy T.} and Leo Cohen and Gooren, {Louis J.G.}",
year = "1989",
month = "6",
day = "1",
doi = "10.1007/BF01543196",
language = "English",
volume = "18",
pages = "217--228",
journal = "Archives of Sexual Behavior",
issn = "0004-0002",
publisher = "Springer New York",
number = "3",

}

Effects of the pure antiandrogen RU 23.903 (anandron) on sexuality, aggression, and mood in male-to-female transsexuals. / van Kemenade, Johannes F.L.M.; Cohen-Kettenis, Peggy T.; Cohen, Leo; Gooren, Louis J.G.

In: Archives of Sexual Behavior, Vol. 18, No. 3, 01.06.1989, p. 217-228.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Effects of the pure antiandrogen RU 23.903 (anandron) on sexuality, aggression, and mood in male-to-female transsexuals

AU - van Kemenade, Johannes F.L.M.

AU - Cohen-Kettenis, Peggy T.

AU - Cohen, Leo

AU - Gooren, Louis J.G.

PY - 1989/6/1

Y1 - 1989/6/1

N2 - Sexuality, aggression, and mood were investigated in 14 presurgical male-to-female transsexuals, undergoing antiandrogenic treatment with anandron, a pure antiandrogen. Subjects were given a test battery the morning prior to treatment onset and after 8 weeks of treatment. In addition they were requested to complete daily forms concerned with sexual behavior and mood. Morning erections and the frequency of thoughts and fantasies about sex decreased after anandron intake. Aggressive feelings were uncorrelated with testosterone level. Moods such as level of energy, feelings of relaxation, fatigue, and feelings of tension and anxiety appeared to fluctuate more as a consequence of anandron intake than did moods such as cheerful, sociable and friendly, gloomy and unhappy, irritated and changeable. The latter remained at a constant level.

AB - Sexuality, aggression, and mood were investigated in 14 presurgical male-to-female transsexuals, undergoing antiandrogenic treatment with anandron, a pure antiandrogen. Subjects were given a test battery the morning prior to treatment onset and after 8 weeks of treatment. In addition they were requested to complete daily forms concerned with sexual behavior and mood. Morning erections and the frequency of thoughts and fantasies about sex decreased after anandron intake. Aggressive feelings were uncorrelated with testosterone level. Moods such as level of energy, feelings of relaxation, fatigue, and feelings of tension and anxiety appeared to fluctuate more as a consequence of anandron intake than did moods such as cheerful, sociable and friendly, gloomy and unhappy, irritated and changeable. The latter remained at a constant level.

KW - aggression

KW - anandron

KW - fantasy

KW - mood

KW - sexuality

KW - transsexuals

UR - http://www.scopus.com/inward/record.url?scp=0024687044&partnerID=8YFLogxK

U2 - 10.1007/BF01543196

DO - 10.1007/BF01543196

M3 - Article

VL - 18

SP - 217

EP - 228

JO - Archives of Sexual Behavior

JF - Archives of Sexual Behavior

SN - 0004-0002

IS - 3

ER -