Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT

Elisa J. de Koning; Nikita L. van der Zwaluw; Janneke P. van Wijngaarden; Evelien Sohl; Elske M. Brouwer-Brolsma; Harm W. J. van Marwijk; Anke W. Enneman; Karin M. A. Swart; Suzanne C. van Dijk; Annelies C. Ham; Nathalie van der Velde; Andre G. Uitterlinden; Brenda W. J. H. Penninx; Petra J. M. Elders; Paul Lips; Rosalie A. M. Dhonukshe-Rutten; Natasja M. van Schoor; Lisette C. P. G. M. de Groot

doi:10.3390/nu8110748

Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT

Elisa J. de Koning, Nikita L. van der Zwaluw, Janneke P. van Wijngaarden, Evelien Sohl, Elske M. Brouwer-Brolsma, Harm W. J. van Marwijk, Anke W. Enneman, Karin M. A. Swart, Suzanne C. van Dijk, Annelies C. Ham, Nathalie van der Velde, Andre G. Uitterlinden, Brenda W. J. H. Penninx, Petra J. M. Elders, Paul Lips, Rosalie A. M. Dhonukshe-Rutten, Natasja M. van Schoor, Lisette C. P. G. M. de Groot

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	E748
Journal	Nutrients
Volume	8
Issue number	11
DOIs	https://doi.org/10.3390/nu8110748
Publication status	Published - Nov 2016

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10.3390/nu8110748

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de Koning, E. J., van der Zwaluw, N. L., van Wijngaarden, J. P., Sohl, E., Brouwer-Brolsma, E. M., van Marwijk, H. W. J., Enneman, A. W., Swart, K. M. A., van Dijk, S. C., Ham, A. C., van der Velde, N., Uitterlinden, A. G., Penninx, B. W. J. H., Elders, P. J. M., Lips, P., Dhonukshe-Rutten, R. A. M., van Schoor, N. M., & de Groot, L. C. P. G. M. (2016). Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT. Nutrients, 8(11), [E748]. https://doi.org/10.3390/nu8110748

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title = "Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT",

keywords = "homocysteine, hyperhomocysteinemia, depressive symptoms, quality of life, vitamin B-12, folic acid, older adults, randomized controlled trial",

author = "{de Koning}, {Elisa J.} and {van der Zwaluw}, {Nikita L.} and {van Wijngaarden}, {Janneke P.} and Evelien Sohl and Brouwer-Brolsma, {Elske M.} and {van Marwijk}, {Harm W. J.} and Enneman, {Anke W.} and Swart, {Karin M. A.} and {van Dijk}, {Suzanne C.} and Ham, {Annelies C.} and {van der Velde}, Nathalie and Uitterlinden, {Andre G.} and Penninx, {Brenda W. J. H.} and Elders, {Petra J. M.} and Paul Lips and Dhonukshe-Rutten, {Rosalie A. M.} and {van Schoor}, {Natasja M.} and {de Groot}, {Lisette C. P. G. M.}",

year = "2016",

month = nov,

doi = "10.3390/nu8110748",

language = "English",

volume = "8",

journal = "Nutrients",

issn = "2072-6643",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "11",

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de Koning, EJ, van der Zwaluw, NL, van Wijngaarden, JP, Sohl, E, Brouwer-Brolsma, EM, van Marwijk, HWJ, Enneman, AW, Swart, KMA, van Dijk, SC, Ham, AC, van der Velde, N, Uitterlinden, AG, Penninx, BWJH , Elders, PJM , Lips, P, Dhonukshe-Rutten, RAM, van Schoor, NM & de Groot, LCPGM 2016, 'Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT', Nutrients, vol. 8, no. 11, E748. https://doi.org/10.3390/nu8110748

Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT. / de Koning, Elisa J.; van der Zwaluw, Nikita L.; van Wijngaarden, Janneke P. et al.

In: Nutrients, Vol. 8, No. 11, E748, 11.2016.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT

AU - de Koning, Elisa J.

AU - van der Zwaluw, Nikita L.

AU - van Wijngaarden, Janneke P.

AU - Sohl, Evelien

AU - Brouwer-Brolsma, Elske M.

AU - van Marwijk, Harm W. J.

AU - Enneman, Anke W.

AU - Swart, Karin M. A.

AU - van Dijk, Suzanne C.

AU - Ham, Annelies C.

AU - van der Velde, Nathalie

AU - Uitterlinden, Andre G.

AU - Penninx, Brenda W. J. H.

AU - Elders, Petra J. M.

AU - Lips, Paul

AU - Dhonukshe-Rutten, Rosalie A. M.

AU - van Schoor, Natasja M.

AU - de Groot, Lisette C. P. G. M.

PY - 2016/11

Y1 - 2016/11

KW - homocysteine

KW - hyperhomocysteinemia

KW - depressive symptoms

KW - quality of life

KW - vitamin B-12

KW - folic acid

KW - older adults

KW - randomized controlled trial

U2 - 10.3390/nu8110748

DO - 10.3390/nu8110748

M3 - Article

C2 - 27886078

VL - 8

JO - Nutrients

JF - Nutrients

SN - 2072-6643

IS - 11

M1 - E748

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de Koning EJ, van der Zwaluw NL, van Wijngaarden JP, Sohl E, Brouwer-Brolsma EM, van Marwijk HWJ et al. Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT. Nutrients. 2016 Nov;8(11):E748. doi: 10.3390/nu8110748